Protein Alignment SERPINA1 and Spn42Dd

DIOPT Version :9

• Sequence 1: NP_000286.3
• Gene: SERPINA1 / 5265
• HGNCID: 8941
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Alignment Length: 383
• Identity: 112/383 - (29%)
• Similarity: 185/383 - (48%)
• Gaps: 37/383 - (9%)

Human    50 ITPNLAEFAFSLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEA 114
            :|....:.:..:|:.|:....:.|:..|||||.|..:|:.:|.:..|..|:...|... :|..||
  Fly    10 VTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP-SEDKEA 73

Human   115 QIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 179
             :...:..||..|...:....|...|.:::::...|...:...|::.:.|||.:::..:...|.:
  Fly    74 -VAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVAAE 137

Human   180 QINDYVEKGTQGKIVDLVK--ELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTTVKV 242
            :||.:|...|.|||..::.  .:..|....|||.|:|||:||..|:...|....|.|....:|.|
  Fly   138 RINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPV 202

Human   243 PMMKRLGMFNIQHCKKLSSWVLLMKYL-GNATAIFFLPDEGK-LQHLENELTHDIITKFLENEDR 305
            .||.::|.|...:.:.|.:.|:.:.|| .|.:...|||.|.: |..||.:     |..|......
  Fly   203 QMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEK-----IVGFARPLVA 262

Human   306 RSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGV-TEEAPLKLSKAVHKAVLTIDEKGT 369
            :...|.|||..|....:||..|.:|||.::|::.:||||: .:::..|:|:..|||.|.::|:|.
  Fly   263 KEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGA 327

Human   370 EAAGA------------MFLEAIPMSIPPEVKFNKPFVFLMIEQNTKSPLFMGKVVNP 415
            |||||            .||.|           :.||.|::.:.||  ..|.|:||:|
  Fly   328 EAAGATSVAVTNRAGFSTFLMA-----------DHPFAFVIRDANT--IYFQGRVVSP 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SERPINA1	NP_000286.3	alpha-1-antitrypsin_like	55..412	CDD:239011	108/373 (29%)
		RCL	368..392		9/35 (26%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	108/372 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010