DRSC/TRiP Functional Genomics Resources

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Protein Alignment SERPINA1 and Serpina1d

DIOPT Version :10

Sequence 1:NP_000286.3 Gene:SERPINA1 / 5265 HGNCID:8941 Length:418 Species:Homo sapiens
Sequence 2:NP_033272.1 Gene:Serpina1d / 20703 MGIID:891968 Length:413 Species:Mus musculus


Alignment Length:136 Identity:29/136 - (21%)
Similarity:58/136 - (42%) Gaps:25/136 - (18%)


- Green bases have known domain annotations that are detailed below.


Human    63 ELNLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLG 127
            |.:.|:.:...|.::.|.|          |||:|..::.||..|  ..:|   ..|:|:...:..
Mouse    12 ETSAAKMENDKKKKVKETK----------KKKKSKVALFTRAAL--RWFC---FSPSDEPFRFPS 61

Human   128 ANVMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTT---EVNMARVYNWDVKRRNKD 189
            ::   :|::.|.:.:.|:.|    |.:...||::....::...|   ||.|....|.:.|....:
Mouse    62 SD---DYEVYEKRMVEEEEL----KEMKQEEEEVVMEEEEVVMTEEEEVVMTEKVNDNTKEEKTE 119

Human   190 DSTKNK 195
            :..|.:
Mouse   120 EEVKKR 125

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SERPINA1NP_000286.3 serpinA1_A1AT 50..417 CDD:381012 29/136 (21%)
RCL 368..392
Serpina1dNP_033272.1 serpinA1_A1AT 44..412 CDD:381012 18/94 (19%)
RCL 368..387
Blue background indicates that the domain is not in the aligned region.

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