DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Nit2 and CG32751

DIOPT Version :9

Sequence 1:	NP_075664.1	Gene:	Nit2 / 52633	MGIID:	1261838	Length:	276	Species:	Mus musculus
Sequence 2:	NP_001284927.1	Gene:	CG32751 / 318189	FlyBaseID:	FBgn0052751	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	63/269 - (23%)
Similarity:	111/269 - (41%)	Gaps:	63/269 - (23%)

- Green bases have known domain annotations that are detailed below.

Mouse     4 FRLALIQLQVSSIKSDNLTRACSLVREAAKQGANIVSLPE-CFNSPYGTTYFPDYAEKI------ 61
            :...:::.:.|:..||||.....:::.......:|:..|| ..||...||:.|:..::|
  Fly    33 YTAGVVEFEPSNELSDNLAGYLEIIQSQNATSTDIIVFPESTLNSAGSTTFVPNPEDQINPCLSD 97

Mouse    62 PG-----ESTQKLSEVAKESSIYLIGG--------SIPEE------DAGKLYNTCSVFGPDGSLL 107
            |.     |....||..|:.:|.|::..        .|||:      :...::||..||...|.::
  Fly    98 PNATYYEEFLVTLSCAARNASKYIVINLTEKQKCEDIPEDTRPCASNGLNVFNTNVVFDRQGVVV 162

Mouse   108 VKHRKIHLFDIDVPGKITFQESKTLSPGDSFSTFDTPY-CKVGLGICYDMRFAELA-QIYAQRGC 170
            .::||:||:     |:   .::.|..|  ..|||:|.: ...|..||:|:.|...| |:..::|.
  Fly   163 SRYRKVHLY-----GE---PKNSTFLP--ELSTFETDFGVTFGHFICFDILFYTPAHQLIVEQGI 217

Mouse   171 QLLVYPGAFNLTTGPAHWELLQRARAVDNQVYVATASPARDDKASYV--AWGHSTVVDPWGQVLT 233
            ...||         ||.|         .:|:...|.:.....||..:  .|.::..|:     |.
  Fly   218 TDFVY---------PAMW---------FSQLPFLTVNGIFSSKAVQIQLGWSYANNVN-----LL 259

Mouse   234 KAGTEETIL 242
            .||..:.|:
  Fly   260 AAGASDPIV 268

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Nit2	NP_075664.1	nit	5..265	CDD:143596	63/268 (24%)
CG32751	NP_001284927.1	biotinidase_like	33..329	CDD:143591	63/269 (23%)
CG32751	NP_001284927.1	Vanin_C	324..503	CDD:408788
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0388
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810