Protein Alignment PHKG1 and PhKgamma

DIOPT Version :9

• Sequence 1: XP_016867813.1
• Gene: PHKG1 / 5260
• HGNCID: 8930
• Length: 432
• Species: Homo sapiens
• Sequence 2: NP_511129.3
• Gene: PhKgamma / 32120
• FlyBaseID: FBgn0011754
• Length: 560
• Species: Drosophila melanogaster
• Alignment Length: 599
• Identity: 218/599 - (36%)
• Similarity: 279/599 - (46%)
• Gaps: 227/599 - (37%)

Human     4 DEALPDSHSAQDFYENYEPKEILGRGVSSVVRRCIHKPTSQEYAVKVIDV---TGGGSFSPEEVR 65
            |:.|||..:|:.||..||||||||||:||.|||||.|.|.:|:|.|:||:   |..|..:|   .
  Fly     7 DDLLPDKDAAKGFYAKYEPKEILGRGISSTVRRCIEKETGKEFAAKIIDLGATTESGETNP---Y 68

Human    66 ELREATLKEVDILRKVSGHPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKI 130
            .:.|||.:|:.|||:|.|||.||.|:|.:|::.|.||||:|..:||||||||..||||||:||.|
  Fly    69 HMLEATRQEISILRQVMGHPYIIDLQDVFESDAFVFLVFELCPKGELFDYLTSVVTLSEKKTRTI 133

Human   131 MRALLEVICTLHKLNIVHRDLKPENILLDDNMNIKLTDFGFSCQLEPGERLRVETGFHHVGQAGL 195
            ||.:.|.:..:|..:||||||||||||||:|.|:|:|||||:.||:.||:|
  Fly   134 MRQIFEGVEYIHAKSIVHRDLKPENILLDENHNVKITDFGFAKQLQEGEKL-------------- 184

Human   196 ELLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEIIECSMNEDHPGYGKEVDMWS 260
                                           :.:||||.|||||.::|:|.|..|||.:|||:|:
  Fly   185 -------------------------------TNLCGTPGYLAPETLKCNMFEGSPGYSQEVDIWA 218

Human   261 TGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTAE 325
            .||||:|||.|.|||||||||:|||.||.|.|.|.||||.|.|:..|||:.:.|||.|..|.|.:
  Fly   219 CGVIMFTLLVGCPPFWHRKQMVMLRNIMEGKYSFTSPEWADISEDPKDLIRKCLVVDPSQRITVK 283

Human   326 EALAHPFF-QQYLVEEVRH---------------------------------------------- 343
            |.|.|||| |..|:.:.||
  Fly   284 EVLRHPFFNQMVLMGDRRHPAPPIAPAQTNSRHLLQPEASSYRFGQLNSSCAGAPNYLYCAPQSS 348

Human   344 ----------------------------------------------------------------- 343
                                                                             
  Fly   349 YSSNRMRDGALDDAGASAASATCHVMSPSNASNSYATNTTANTSNSALASASSHKTLTAMVYYQQ 413

Human   344 --------------------------------------------------------FSPRGKFKV 352
                                                                    |:.|.||:.
  Fly   414 QPQQHQTQQQQQQYQQQQTTQLPVQLQLQHPLLQTGGDGKQSVYAPPTVQLRKQSRFNARKKFQF 478

Human   353 IALTVLASVRIYYQYRRVK----PVTREIVIRDPYALRPLRRLIDAYAFRIYGHWVKKGQQQNRA 413
            ..|.:.|.:||    ||::    |:..|..|||||.::.||::||..|||:||||||||:.||||
  Fly   479 AILVIRAIIRI----RRLRFTAEPLHVEEAIRDPYRVKVLRKVIDGCAFRVYGHWVKKGEGQNRA 539

Human   414 ALFENTPKAVLLSL 427
            |||||||:..|.:|
  Fly   540 ALFENTPRTELHAL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHKG1	XP_016867813.1	None
PhKgamma	NP_511129.3	STKc_PhKG	19..291	CDD:270995	162/319 (51%)
		S_TKc	23..291	CDD:214567	160/315 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	342	1.000	Domainoid score	I1076
eggNOG	1	0.900	-	-		E1_KOG0599
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	440	1.000	Inparanoid score	I1671
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48604
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	1	1.000	-	-		FOG0002585
OrthoInspector	1	1.000	-	-		otm40794
orthoMCL	1	0.900	-	-		OOG6_105085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4277
SonicParanoid	1	1.000	-	-		X1942
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770