Protein Alignment PHKA2 and Phka2

DIOPT Version :10

• Sequence 1: NP_001427734.1
• Gene: PHKA2 / 5256
• HGNCID: 8926
• Length: 1243
• Species: Homo sapiens
• Sequence 2: NP_001382568.1
• Gene: Phka2 / 678739
• RGDID: 1596945
• Length: 1217
• Species: Rattus norvegicus
• Alignment Length: 1243
• Identity: 1118/1243 - (89%)
• Similarity: 1166/1243 - (93%)
• Gaps: 26/1243 - (2%)

Human     1 MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHEQKDAWVRDNIYSILAVWGLGMAYRKNA 65
            |||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||
  Rat     1 MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHDQKDAWVRDNIYSILAVWGLGMAYRKNA 65

Human    66 DRDEDKAKAYELEQNVVKLMRGLLQCMMRQVAKVEKFKHTQSTKDSLHAKYNTATCGTVVGDDQW 130
            |||||||||||||||||||||||||||||||.||||||||||||||||||||||||.||||||||
  Rat    66 DRDEDKAKAYELEQNVVKLMRGLLQCMMRQVDKVEKFKHTQSTKDSLHAKYNTATCSTVVGDDQW 130

Human   131 GHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIP 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 GHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIP 195

Human   196 ELNASSVGMAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLL 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 ELNASSVGMAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLL 260

Human   261 SIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPNRLHYDPAELKLFENIE 325
            |||||||||||||:||||||||||||||||||||||||||||||||||:||||||||||||||||
  Rat   261 SIISFPAFAVEDVHLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPHRLHYDPAELKLFENIE 325

Human   326 CEWPVFWTYFIIDGVFSGDAVQVQEYREALEGILIRGKNGIRLVPELYAVPPNKVDEEYKNPHTV 390
            |||||||||.||||||:|||||||||||||||||||||:||.|||||||:||:||||||||||||
  Rat   326 CEWPVFWTYLIIDGVFNGDAVQVQEYREALEGILIRGKDGIHLVPELYAIPPDKVDEEYKNPHTV 390

Human   391 DRVPMGKVPHLWGQSLYILSSLLAEGFLAAGEIDPLNRRFSTSVKPDVVVQVTVLAENNHIKDLL 455
            ||:|:||:|||||||||||||||||||||.||||||||||||||||||||||.|||||:|||.||
  Rat   391 DRIPLGKLPHLWGQSLYILSSLLAEGFLATGEIDPLNRRFSTSVKPDVVVQVAVLAENSHIKGLL 455

Human   456 RKHGVNVQSIADIHPIQVQPGRILSHIYAKLGRNKNMNLSGRPYRHIGVLGTSKLYVIRNQIFTF 520
            ::||:|||||||:|||:|||||||||||||||:||||.||||||||||||||||||||||.||||
  Rat   456 KQHGINVQSIADVHPIRVQPGRILSHIYAKLGQNKNMKLSGRPYRHIGVLGTSKLYVIRNHIFTF 520

Human   521 TPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPISRTMLTNDGSDIHSAVLST 585
            |||||||||||||||||||||||||||||||||||||||||||||::.|||||||||||.|||||
  Rat   521 TPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPVTHTMLTNDGSDIHPAVLST 585

Human   586 IRKLEDGYFGGARVKLGNLSEFLTTSFYTYLTFLDPDCDEKLFDNASEGTFSPDSDSDLVGYLED 650
            |||||||||||||||||.|:|||||||||||||||||||||||.:.|:.:|||||:|||.|||||
  Rat   586 IRKLEDGYFGGARVKLGILAEFLTTSFYTYLTFLDPDCDEKLFGDISDRSFSPDSESDLGGYLED 650

Human   651 TCNQESQDELDHYINHLLQSTSLRSYLPPLCKNTEDRHVFSAIHSTRDILSVMAKAKGLEVPFVP 715
            :.:||||||||.||:||||||||:.|||||||.:||.|||||:|||||||||||||||||.||.|
  Rat   651 SSHQESQDELDQYISHLLQSTSLKCYLPPLCKKSEDSHVFSAVHSTRDILSVMAKAKGLETPFFP 715

Human   716 MTLPTKVLSAHRKSLNLVDSPQPLLEKVPESDFQWPRDDHGDVDCEKLVEQLKDCSNLQDQADIL 780
            |.|||:|||.|||||||||||||.|:|.||.|:||||||..:|||||||.|||||||||||||||
  Rat   716 MILPTRVLSGHRKSLNLVDSPQPFLKKTPEYDYQWPRDDQDEVDCEKLVGQLKDCSNLQDQADIL 780

Human   781 YILYVIKGPSWDTNLSGQHGVTVQNLLGELYGKAGLNQEWGLIRYISGLLRKKVEVLAEACTDLL 845
            |||||||||.|||||.|||||||.:|||||||||||||||.||||||||||||||||||||.|||
  Rat   781 YILYVIKGPRWDTNLFGQHGVTVHSLLGELYGKAGLNQEWSLIRYISGLLRKKVEVLAEACADLL 845

Human   846 SHQKQLTVGLPPEPREKIISAPLPPEELTKLIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFV 910
            |||||||||||||||||.||.||||||||:||||||||||||||||||||||||||||||||||.
  Rat   846 SHQKQLTVGLPPEPREKTISTPLPPEELTELIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFA 910

Human   911 EMLRLRIGLIIQVMATELARSLNCSGEEASESLMNLSPFDMKNLLHHILSGKEFGVERSVRPIHS 975
            ||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
  Rat   911 EMLRLRIGLIIQVMATELARSLNCSGEEASESLMNLSPFDMKSLLHHILSGKEFGVERSVRPIHS 975

Human   976 STSSPTISIHEVGHTGVTKTERSGINRLRSEMKQMTRRFSADEQFFSVGQAASSSAHSSKSAVTV 1040
            |.|||.|||||||||||||||||||:|||||||||.||.|||||
  Rat   976 SMSSPAISIHEVGHTGVTKTERSGISRLRSEMKQMNRRASADEQ--------------------- 1019

Human  1041 PRDYCRSSTPSSPTGTSSSDSGGHHIGWGERQGQWLRRRRLDGAINRVPVGFYQRVWKILQKCHG 1105
                 |||||||||||||:||||||:||||:||||||||||||||||||||||||||||||||||
  Rat  1020 -----RSSTPSSPTGTSSTDSGGHHLGWGEQQGQWLRRRRLDGAINRVPVGFYQRVWKILQKCHG 1079

Human  1106 LSIDGYVLPSSTTREMTPHEIKFAVHVESVLNRVPQPEYRQLLVEAIMVLTLLSDTEMTSIGGII 1170
            |||||||||||||:||||.|||||||||||||||.|||||||||||||||||||||||.||||||
  Rat  1080 LSIDGYVLPSSTTQEMTPCEIKFAVHVESVLNRVSQPEYRQLLVEAIMVLTLLSDTEMDSIGGII 1144

Human  1171 HVDQIVQMASQLFLQDQVSIGAMDTLEKDQATGICHFFYDSAPSGAYGTMTYLTRAVASYLQELL 1235
            |||||||:|:|||||||||.|..|.|||||||||||.|||||||||||||||||:||||:||:||
  Rat  1145 HVDQIVQLANQLFLQDQVSFGTTDILEKDQATGICHLFYDSAPSGAYGTMTYLTKAVASHLQDLL 1209

Human  1236 PNSGCQMQ 1243
            |:||||||
  Rat  1210 PSSGCQMQ 1217

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHKA2	NP_001427734.1	Calmodulin-binding. /evidence=ECO:0000255	807..837		28/29 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	972..998		23/25 (92%)
		Calmodulin-binding. /evidence=ECO:0000255	1067..1107		38/39 (97%)
Phka2	NP_001382568.1	Glyco_hydro_15	8..>439	CDD:395586	415/430 (97%)
		Bac_rhamnosid6H	<802..919	CDD:481215	108/116 (93%)
		KPBB_C	930..>1129	CDD:437124	186/224 (83%)