Protein Alignment PHKA2 and Phka2

DIOPT Version :10

• Sequence 1: NP_001427734.1
• Gene: PHKA2 / 5256
• HGNCID: 8926
• Length: 1243
• Species: Homo sapiens
• Sequence 2: XP_006528742.1
• Gene: Phka2 / 110094
• MGIID: 97577
• Length: 1240
• Species: Mus musculus
• Alignment Length: 1243
• Identity: 1122/1243 - (90%)
• Similarity: 1171/1243 - (94%)
• Gaps: 8/1243 - (0%)

Human     1 MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHEQKDAWVRDNIYSILAVWGLGMAYRKNA 65
            |||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||||
Mouse     6 MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHDQKDAWVRDNIYSILAVWGLGMAYRKNA 70

Human    66 DRDEDKAKAYELEQNVVKLMRGLLQCMMRQVAKVEKFKHTQSTKDSLHAKYNTATCGTVVGDDQW 130
            |||||||||||||||||||||||||||||||.||||||||||||||||||||||||.||||||||
Mouse    71 DRDEDKAKAYELEQNVVKLMRGLLQCMMRQVDKVEKFKHTQSTKDSLHAKYNTATCSTVVGDDQW 135

Human   131 GHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIP 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   136 GHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIP 200

Human   196 ELNASSVGMAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLL 260
            ||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   201 ELNASSVGVAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLL 265

Human   261 SIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPNRLHYDPAELKLFENIE 325
            ||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||||
Mouse   266 SIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPHRLHYDPAELKLFENIE 330

Human   326 CEWPVFWTYFIIDGVFSGDAVQVQEYREALEGILIRGKNGIRLVPELYAVPPNKVDEEYKNPHTV 390
            |||||||||.||||:|:|||||||||||||||||||||:||.|||||||:||:||||||||||||
Mouse   331 CEWPVFWTYLIIDGIFNGDAVQVQEYREALEGILIRGKDGIHLVPELYAIPPDKVDEEYKNPHTV 395

Human   391 DRVPMGKVPHLWGQSLYILSSLLAEGFLAAGEIDPLNRRFSTSVKPDVVVQVTVLAENNHIKDLL 455
            ||||:||:|||||||||||||||||||||.||||||||||||||||||||||.|||||:|||.||
Mouse   396 DRVPLGKLPHLWGQSLYILSSLLAEGFLATGEIDPLNRRFSTSVKPDVVVQVAVLAENSHIKGLL 460

Human   456 RKHGVNVQSIADIHPIQVQPGRILSHIYAKLGRNKNMNLSGRPYRHIGVLGTSKLYVIRNQIFTF 520
            ::||:.||||||:|||:||||||||||||||||||||.||||||||||||||||||||||.||||
Mouse   461 KEHGMTVQSIADVHPIRVQPGRILSHIYAKLGRNKNMKLSGRPYRHIGVLGTSKLYVIRNHIFTF 525

Human   521 TPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPISRTMLTNDGSDIHSAVLST 585
            |||||||||||||||||||||||||||||||||||||||||||||::.|||||||||||.|||||
Mouse   526 TPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPVTHTMLTNDGSDIHPAVLST 590

Human   586 IRKLEDGYFGGARVKLGNLSEFLTTSFYTYLTFLDPDCDEKLFDNASEGTFSPDSDSDLVGYLED 650
            |||||||||||||||||||:|||||||||:|||||||||||||.:.::.:|||||:.||.|||||
Mouse   591 IRKLEDGYFGGARVKLGNLAEFLTTSFYTHLTFLDPDCDEKLFGDITDRSFSPDSEPDLGGYLED 655

Human   651 TCNQESQDELDHYINHLLQSTSLRSYLPPLCKNTEDRHVFSAIHSTRDILSVMAKAKGLEVPFVP 715
            :..||||||||.||:||||||||:.|||||||.:||.|.|||||||||||||||||||||..|.|
Mouse   656 SSPQESQDELDQYISHLLQSTSLKCYLPPLCKKSEDSHFFSAIHSTRDILSVMAKAKGLETTFFP 720

Human   716 MTLPTKVLSAHRKSLNLVDSPQPLLEKVPESDFQWPRDDHGDVDCEKLVEQLKDCSNLQDQADIL 780
            |.|||||||.|||||||||||||||:..||.|:|||||||.:|||||||.|||||||||||||||
Mouse   721 MILPTKVLSGHRKSLNLVDSPQPLLKTTPEYDYQWPRDDHDEVDCEKLVGQLKDCSNLQDQADIL 785

Human   781 YILYVIKGPSWDTNLSGQHGVTVQNLLGELYGKAGLNQEWGLIRYISGLLRKKVEVLAEACTDLL 845
            |||||:|||.|||||.|||||||.:||.||||||||||||.||||||||||||||||||||.|||
Mouse   786 YILYVMKGPRWDTNLFGQHGVTVHSLLSELYGKAGLNQEWSLIRYISGLLRKKVEVLAEACADLL 850

Human   846 SHQKQLTVGLPPEPREKIISAPLPPEELTKLIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFV 910
            |||||||||||||||||.||.||||||||:||||||||||||||||||||||||||||||||||.
Mouse   851 SHQKQLTVGLPPEPREKTISTPLPPEELTELIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFA 915

Human   911 EMLRLRIGLIIQVMATELARSLNCSGEEASESLMNLSPFDMKNLLHHILSGKEFGVERSVRPIHS 975
            ||||||||||||||||||||||||||:|||||||||||||||:||||||||||||||||||||||
Mouse   916 EMLRLRIGLIIQVMATELARSLNCSGKEASESLMNLSPFDMKSLLHHILSGKEFGVERSVRPIHS 980

Human   976 STSSPTISIHEVGHTGVTKTERSGINRLRSEMKQMTRRFSADEQFFSVGQAASSSAHSSKSAVTV 1040
            |.|||.||||||||||.||||||||.|||||||||.||.|||||||.:||..|:|.||.||.
Mouse   981 SMSSPAISIHEVGHTGATKTERSGITRLRSEMKQMNRRASADEQFFPLGQTMSNSLHSIKSV--- 1042

Human  1041 PRDYCRSSTPSSPTGTSSSDSGGHHIGWGERQGQWLRRRRLDGAINRVPVGFYQRVWKILQKCHG 1105
                 |||||||||||||:||||.|:||||:|||||||||||||||||||||||:||||||||||
Mouse  1043 -----RSSTPSSPTGTSSTDSGGQHLGWGEQQGQWLRRRRLDGAINRVPVGFYQKVWKILQKCHG 1102

Human  1106 LSIDGYVLPSSTTREMTPHEIKFAVHVESVLNRVPQPEYRQLLVEAIMVLTLLSDTEMTSIGGII 1170
            |||||||||||||:||||.|||||||||||||||.|||||||||||||||||||||||.||||||
Mouse  1103 LSIDGYVLPSSTTQEMTPCEIKFAVHVESVLNRVSQPEYRQLLVEAIMVLTLLSDTEMDSIGGII 1167

Human  1171 HVDQIVQMASQLFLQDQVSIGAMDTLEKDQATGICHFFYDSAPSGAYGTMTYLTRAVASYLQELL 1235
            |||||||:|:|||||||||.|..|.|||||||||||.|||||||||||||||||:||||:|||||
Mouse  1168 HVDQIVQLANQLFLQDQVSFGTTDILEKDQATGICHLFYDSAPSGAYGTMTYLTKAVASHLQELL 1232

Human  1236 PNSGCQMQ 1243
            |:||||||
Mouse  1233 PSSGCQMQ 1240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHKA2	NP_001427734.1	Calmodulin-binding. /evidence=ECO:0000255	807..837		27/29 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	972..998		22/25 (88%)
		Calmodulin-binding. /evidence=ECO:0000255	1067..1107		37/39 (95%)
Phka2	XP_006528742.1	Glyco_hydro_15	13..>444	CDD:395586	415/430 (97%)
		Bac_rhamnosid6H	<807..924	CDD:481215	107/116 (92%)
		KPBB_C	935..>1152	CDD:437124	192/224 (86%)