Protein Alignment ATP6V1B1 and VMA2

DIOPT Version :10

• Sequence 1: XP_011531209.1
• Gene: ATP6V1B1 / 525
• HGNCID: 853
• Length: 553
• Species: Homo sapiens
• Sequence 2: NP_009685.3
• Gene: VMA2 / 852424
• SGDID: S000000331
• Length: 517
• Species: Saccharomyces cerevisiae
• Alignment Length: 456
• Identity: 361/456 - (79%)
• Similarity: 402/456 - (88%)
• Gaps: 3/456 - (0%)

Human    99 FAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLG 163
            |.:|.|||:.||||||.|.|||||:.|.:|||||||||||||.:|||.||||:.||.||||||||
Yeast    46 FPRYNEIVNLTLPDGTVRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLG 110

Human   164 RVFNGSGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSA 228
            |:|:|||:|||.||.|.|||:|||||.||||::||||||||.||:|.||.|||||||||||||||
Yeast   111 RIFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTMNSIARGQKIPIFSA 175

Human   229 AGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCL 293
            :||||||||||||||||||:.:|.|.|.|::||:|||||||||:|||||||.|||:||::....|
Yeast   176 SGLPHNEIAAQICRQAGLVRPTKDVHDGHEENFSIVFAAMGVNLETARFFKQDFEENGSLERTSL 240

Human   294 FLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFP 358
            ||||||||||||||||||||||||:||||.|:|||.|||||||||:|||||||||||||||||:|
Yeast   241 FLNLANDPTIERIITPRLALTTAEYLAYQTERHVLTILTDMSSYADALREVSAAREEVPGRRGYP 305

Human   359 GYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIY 423
            |||||||:||||||||||||.|||||||||||||||||||||||||:||||||:|||||||:.||
Yeast   306 GYMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIY 370

Human   424 PPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEF 488
            |||||||||||||||||||||||||||||||||||.||||||..|||||||||||:.||.|.|||
Yeast   371 PPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVGEEALSIEDKLSLEF 435

Human   489 LQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFY--SREGALQDLA-PD 550
            |:||||.||.||.||:|:||||||..|.||||:|||||.||...::||||  :|:.|.:|.. ||
Yeast   436 LEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKEMLNRISPKILDEFYDRARDDADEDEEDPD 500

Human   551 T 551
            |
Yeast   501 T 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V1B1	XP_011531209.1	V-ATPase_V1_B	99..543	CDD:273410	356/445 (80%)
VMA2	NP_009685.3	V-ATPase_V1_B	27..485	CDD:273410	353/438 (81%)