Protein Alignment ATP6V1B1 and vma2

DIOPT Version :10

• Sequence 1: XP_011531209.1
• Gene: ATP6V1B1 / 525
• HGNCID: 853
• Length: 553
• Species: Homo sapiens
• Sequence 2: NP_594623.1
• Gene: vma2 / 2543408
• PomBaseID: SPAC637.05C
• Length: 503
• Species: Schizosaccharomyces pombe
• Alignment Length: 451
• Identity: 358/451 - (79%)
• Similarity: 401/451 - (88%)
• Gaps: 1/451 - (0%)

Human   101 QYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLGRV 165
            ||.|||:..||||:.||||||||||.||||||||||||:|.||||.:|||..:|.||||||||||
pombe    44 QYNEIVNLNLPDGSVRSGQVLEVAGHKAIVQVFEGTSGVDVRKTTIDFTGHSMRIPVSEDMLGRV 108

Human   166 FNGSGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSAAG 230
            |||||.||||||.::|||:|||||.||||::|||||||||||||.||.:||||||||||||||||
pombe   109 FNGSGLPIDKGPNLLAEDYLDINGSPINPYARIYPEEMIQTGISSIDGLNSIARGQKIPIFSAAG 173

Human   231 LPHNEIAAQICRQAGLVKK-SKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCLF 294
            ||||||||||||||||||: :|.|.|.|:|||:|||||||||:||||||:.|||:||:...|.||
pombe   174 LPHNEIAAQICRQAGLVKRPTKDVHDGHEDNFSIVFAAMGVNLETARFFQRDFEENGSFERVTLF 238

Human   295 LNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFPG 359
            |||||||||||||||||||:.:||||||.|||||.|||||:|||:|||||||||||||||||:||
pombe   239 LNLANDPTIERIITPRLALSASEFLAYQTEKHVLTILTDMTSYADALREVSAAREEVPGRRGYPG 303

Human   360 YMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIYP 424
            ||||||:||||||||||||.|||||||||||||||||||||||||:||||||:|||||||..|||
pombe   304 YMYTDLSTIYERAGRVEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNNAIYP 368

Human   425 PINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEFL 489
            ||||||||||||||||||||||.|||||||||||.||||:|..:||:|||||||:.||.|.||||
pombe   369 PINVLPSLSRLMKSAIGEGMTRNDHGDVSNQLYAMYAIGRDAASMKSVVGEEALSQEDRLALEFL 433

Human   490 QKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSREGALQDLAPD 550
            .||||.||:||.||||::||:|||.|.||||||:|||.|||:.::|::|||..|..:.:.|
pombe   434 GKFEKTFISQGAYENRTIFETLDLAWSLLRIFPREMLTRIPKKILDQYYSRSSAYTESSKD 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V1B1	XP_011531209.1	V-ATPase_V1_B	99..543	CDD:273410	356/442 (81%)
vma2	NP_594623.1	V-ATPase_V1_B	23..488	CDD:273410	356/443 (80%)