Protein Alignment ATP6V1B1 and vha-12

DIOPT Version :10

• Sequence 1: XP_011531209.1
• Gene: ATP6V1B1 / 525
• HGNCID: 853
• Length: 553
• Species: Homo sapiens
• Sequence 2: NP_508711.1
• Gene: vha-12 / 180692
• WormBaseID: WBGene00006921
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 445
• Identity: 380/445 - (85%)
• Similarity: 412/445 - (92%)
• Gaps: 2/445 - (0%)

Human    99 FAQYAEIVHFTLPDGTQRSGQVLEVAGTKAIVQVFEGTSGIDARKTTCEFTGDILRTPVSEDMLG 163
            |.|::|||..|||||::|||||||::..||:||||||||||||:.|.||||||||||||||||||
 Worm    47 FPQFSEIVKITLPDGSKRSGQVLEISKNKAVVQVFEGTSGIDAKNTICEFTGDILRTPVSEDMLG 111

Human   164 RVFNGSGKPIDKGPVVMAEDFLDINGQPINPHSRIYPEEMIQTGISPIDVMNSIARGQKIPIFSA 228
            |:||||||||||||.|:||||||||||||||.||||||||||||||.||||||||||||||||||
 Worm   112 RIFNGSGKPIDKGPPVLAEDFLDINGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSA 176

Human   229 AGLPHNEIAAQICRQAGLVKKSKAVLDYHDDNFAIVFAAMGVNMETARFFKSDFEQNGTMGNVCL 293
            :|||||||||||.||.|||:....  .:...||||||||||||||||||||.|||:||:|.||||
 Worm   177 SGLPHNEIAAQIVRQGGLVQLPDR--PHEQTNFAIVFAAMGVNMETARFFKQDFEENGSMENVCL 239

Human   294 FLNLANDPTIERIITPRLALTTAEFLAYQCEKHVLVILTDMSSYAEALREVSAAREEVPGRRGFP 358
            |||||||||||||||||:|||:||||||||:|||||:||||||||||||||||||||||||||||
 Worm   240 FLNLANDPTIERIITPRIALTSAEFLAYQCKKHVLVVLTDMSSYAEALREVSAAREEVPGRRGFP 304

Human   359 GYMYTDLATIYERAGRVEGRGGSITQIPILTMPNDDITHPIPDLTGFITEGQIYVDRQLHNRQIY 423
            ||||||||||||||||||||.|||||||||||||||||||||||||:|||||||||||||||.||
 Worm   305 GYMYTDLATIYERAGRVEGRDGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRLIY 369

Human   424 PPINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYACYAIGKDVQAMKAVVGEEALTSEDLLYLEF 488
            |||||||||||||||||||||||:||.||||||||||||||||||||||||||||:|:|||||||
 Worm   370 PPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIGKDVQAMKAVVGEEALSSDDLLYLEF 434

Human   489 LQKFEKNFINQGPYENRSVFESLDLGWKLLRIFPKEMLKRIPQAVIDEFYSREGA 543
            |.|||||||.||.|||||||||||:||:||||||:|||||||::.::::|.|.||
 Worm   435 LTKFEKNFITQGHYENRSVFESLDIGWQLLRIFPREMLKRIPESTLEKYYPRGGA 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ATP6V1B1	XP_011531209.1	V-ATPase_V1_B	99..543	CDD:273410	378/443 (85%)
vha-12	NP_508711.1	V-ATPase_V1_B	29..489	CDD:273410	378/443 (85%)