Protein Alignment PHB1 and Stoml2

DIOPT Version :10

• Sequence 1: NP_002625.1
• Gene: PHB1 / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_611853.2
• Gene: Stoml2 / 37807
• FlyBaseID: FBgn0034936
• Length: 366
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 58/244 - (23%)
• Similarity: 98/244 - (40%)
• Gaps: 66/244 - (27%)

Human    41 RFRGVQDIVVGEGTHFLIP------WVQ--KPIIFDCRSRPRNVP---VITGSKDLQNVNITLRI 94
            ||..:.|    .|.:.|:|      :||  |.|..|       ||   .||..      |:||.|
  Fly    59 RFHRILD----PGLNILVPVADKIKYVQSLKEIAID-------VPKQSAITSD------NVTLSI 106

Human    95 ---LFRPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTE 156
               |:..:.....   .|.|.:..|..:..:....::|.:.:....::..:||.::..:.|.:.:
  Fly   107 DGVLYLRIIDPYK---ASYGVEDPEFAITQLAQTTMRSELGKMSMDKVFRERESLNVSIVDSINK 168

Human   157 RAATFGLI-----LDDVSLTHLTFGKEFTEAVEAKQVAQQEAERARFVVEKAEQQKKAAIISAEG 216
            .:..:|:.     :.|:.|.        |...||.|: |.||||          :|:|||:.:||
  Fly   169 ASEAWGIACLRYEIRDIRLP--------TRVHEAMQM-QVEAER----------RKRAAILESEG 214

Human   217 DSKAAELIANS------LATAGDGLIELRKL--EAAEDIAYQLSRSRNI 257
            ..:|...||..      ||:..:....:.|.  |||..||...:|:|::
  Fly   215 VREAEINIAEGKRKSRILASEAERQEHINKASGEAAAIIAVADARARSL 263

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHB1	NP_002625.1	SPFH_prohibitin	27..221	CDD:259799	45/198 (23%)
Stoml2	NP_611853.2	HflC	41..318	CDD:440099	58/244 (24%)