Protein Alignment PHB1 and CG33253

DIOPT Version :10

• Sequence 1: NP_002625.1
• Gene: PHB1 / 5245
• HGNCID: 8912
• Length: 272
• Species: Homo sapiens
• Sequence 2: NP_001259699.1
• Gene: CG33253 / 2768889
• FlyBaseID: FBgn0030992
• Length: 414
• Species: Drosophila melanogaster
• Alignment Length: 243
• Identity: 61/243 - (25%)
• Similarity: 107/243 - (44%)
• Gaps: 38/243 - (15%)

Human    35 RAVIFDRFRGVQDIVVGEGTHFLIPWVQKPIIFDCRSRPRNVP---VITGSKDLQNVNITLRILF 96
            |||||...|.......|.|..|::|.|......|.|:...:||   |:  |||...|.:...:.:
  Fly   101 RAVIFRMGRLRSGGARGPGVFFVLPCVDDYYPVDLRTVSFDVPPQEVL--SKDSVTVTVDAVVYY 163

Human    97 RPVASQLPRIFTSIGEDYDERVLPSITTEILKSVVARFDAGELITQRELVSRQVSDDLTERAATF 161
            | ::..|..:.......:...:|.:.|   |::|:...:..||:|:||.:|..:...|.|....:
  Fly   164 R-ISDPLKAVIQVYNYSHSTSLLAATT---LRNVLGTRNLSELLTERETISHTMQMSLDEATDPW 224

Human   162 GLILDDVSLTHLTFGKEFTEAVEAKQVAQQEA-ERARFVVEKAEQQKKAAIISAEGDSKAAELI- 224
            |:.:               |.||.|.|:...| :||.....:|.::.:|.:|:|||:.|::..:
  Fly   225 GVKV---------------ERVEIKDVSLPTALQRAMAAEAEAAREARAKVIAAEGEMKSSRALR 274

Human   225 -ANSLATAGDGLIELRKLEAAEDIAYQLSRSRNITYLPAGQSVLLQLP 271
             |:.:.:|....::||.|:....|    |..:|.|       ::..||
  Fly   275 EASEIISASPSALQLRYLQTLSSI----STEKNST-------IIFPLP 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHB1	NP_002625.1	SPFH_prohibitin	27..221	CDD:259799	50/189 (26%)
CG33253	NP_001259699.1	SPFH_SLP-4	112..319	CDD:259813	55/232 (24%)