Protein Alignment PGK1 and Pgk1

DIOPT Version :10

• Sequence 1: NP_000282.1
• Gene: PGK1 / 5230
• HGNCID: 8896
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_445743.2
• Gene: Pgk1 / 24644
• RGDID: 619878
• Length: 417
• Species: Rattus norvegicus
• Alignment Length: 417
• Identity: 406/417 - (97%)
• Similarity: 412/417 - (98%)
• Gaps: 0/417 - (0%)

Human     1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLG 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLG 65

Human    66 RPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEG 130
            |||||||||||||||||.||||||||||||||||||.|||.||||||||:|||||||||||||||
  Rat    66 RPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGSEVENACANPAAGTVILLENLRFHVEEEG 130

Human   131 KGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELN 195
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 KGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELN 195

Human   196 YFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDE 260
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||
  Rat   196 YFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDE 260

Human   261 EGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYA 325
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||.|||||||
  Rat   261 EGAKIVKDLMAKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYA 325

Human   326 EAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVS 390
            |||.||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||
  Rat   326 EAVARAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVS 390

Human   391 HVSTGGGASLELLEGKVLPGVDALSNI 417
            ||||||||||||||||||||||||||:
  Rat   391 HVSTGGGASLELLEGKVLPGVDALSNV 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGK1	NP_000282.1	PTZ00005	3..417	CDD:173310	403/413 (98%)
		Mitochondrial targeting region exposed following cis-trans isomerization by PIN1 and recognized by the TOM complex for mitochondrial translocation of the protein. /evidence=ECO:0000269|PubMed:26942675	38..43		4/4 (100%)
Pgk1	NP_445743.2	PTZ00005	3..416	CDD:173310	402/412 (98%)
		Mitochondrial targeting region exposed following cis-trans isomerization by PIN1 and recognized by the TOM complex for mitochondrial translocation of the protein. /evidence=ECO:0000250|UniProtKB:P00558	38..43		4/4 (100%)