Protein Alignment PGK1 and Pgk1

DIOPT Version :10

• Sequence 1: NP_000282.1
• Gene: PGK1 / 5230
• HGNCID: 8896
• Length: 417
• Species: Homo sapiens
• Sequence 2: NP_032854.2
• Gene: Pgk1 / 18655
• MGIID: 97555
• Length: 417
• Species: Mus musculus
• Alignment Length: 417
• Identity: 408/417 - (97%)
• Similarity: 413/417 - (99%)
• Gaps: 0/417 - (0%)

Human     1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLG 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLG 65

Human    66 RPDGVPMPDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEG 130
            |||||||||||||||||.||||||||||||||||||||||.||||||||:|||||||||||||||
Mouse    66 RPDGVPMPDKYSLEPVAAELKSLLGKDVLFLKDCVGPEVENACANPAAGTVILLENLRFHVEEEG 130

Human   131 KGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELN 195
            |||||||||||||||||:|||||||||||||||||||||||||||||||||||||||||||||||
Mouse   131 KGKDASGNKVKAEPAKIDAFRASLSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELN 195

Human   196 YFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDE 260
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:||
Mouse   196 YFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFLKVLNNMEIGTSLYDE 260

Human   261 EGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYA 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||.|||||||
Mouse   261 EGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGTESSKKYA 325

Human   326 EAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVS 390
            |||.||||||||||||||||||||||||:||||||||||||||||||||||||||||||||||||
Mouse   326 EAVGRAKQIVWNGPVGVFEWEAFARGTKSLMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVS 390

Human   391 HVSTGGGASLELLEGKVLPGVDALSNI 417
            ||||||||||||||||||||||||||:
Mouse   391 HVSTGGGASLELLEGKVLPGVDALSNV 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PGK1	NP_000282.1	PTZ00005	3..417	CDD:173310	405/413 (98%)
		Mitochondrial targeting region exposed following cis-trans isomerization by PIN1 and recognized by the TOM complex for mitochondrial translocation of the protein. /evidence=ECO:0000269|PubMed:26942675	38..43		4/4 (100%)
Pgk1	NP_032854.2	PTZ00005	3..416	CDD:173310	404/412 (98%)
		Mitochondrial targeting region exposed following cis-trans isomerization by PIN1 and recognized by the TOM complex for mitochondrial translocation of the protein. /evidence=ECO:0000250|UniProtKB:P00558	38..43		4/4 (100%)