Protein Alignment PEX13 and pex13

DIOPT Version :10

• Sequence 1: NP_002609.1
• Gene: PEX13 / 5194
• HGNCID: 8855
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_956939.1
• Gene: pex13 / 393618
• ZFINID: ZDB-GENE-040426-1544
• Length: 416
• Species: Danio rerio
• Alignment Length: 424
• Identity: 256/424 - (60%)
• Similarity: 303/424 - (71%)
• Gaps: 38/424 - (8%)

Human     7 PPPKPWETRRIPGAGPGPGPGPTFQSADLGPTLMTRP---GQPALTRVPPPILPRPSQQTGSSSV 68
            ||||||| |||||....|   ..::|.|.|....:.|   |.|.||||.|||.|||.:|
Zfish     4 PPPKPWE-RRIPGTITAP---LNYRSTDFGSVSQSGPSGSGPPVLTRVVPPIPPRPVRQ------ 58

Human    69 NTFRPAYSSFSSGYGAYGNSFYGGYSPYSY-GY---NGLGYNRLR-VDDLPPSRFVQQAEESSRG 128
             ::||.||||.|.|..||||.||||||||| ||   .||||||.. :|::|||||||||||||||
Zfish    59 -SYRPTYSSFPSSYSPYGNSMYGGYSPYSYSGYGVGGGLGYNRFNTMDEIPPSRFVQQAEESSRG 122

Human   129 AFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFTKVFSAFALVRTIRYLYR 193
            ||||||||||||:||||||||||||||||||||||||||||||:||||||.||||||||:|||||
Zfish   123 AFQSIESIVHAFSSVSMMMDATFSAVYNSFRAVLDVANHFSRLRIHFTKVLSAFALVRTLRYLYR 187

Human   194 RLQRMLGLRRGSENEDLWAESEGTVACL--------GAEDRAATSAKSWPIFLFFAVILGGPYLI 250
            ||||::|||:|||.:||||:|..:.:.:        |.|:....|.|||||||||||:|||||||
Zfish   188 RLQRLMGLRQGSEVDDLWADSAASSSVVSASGARGAGVEEPGVNSVKSWPIFLFFAVVLGGPYLI 252

Human   251 WKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAGDMLNLALKEQQPKVRGWLL 315
            |:|||:......::.|||||||||||||.||||.|.||||||.:||||||||.|||||:||||||
Zfish   253 WRLLSSAEGAEENATNWASGEDDHVVARVEYDFTAASEEEISVQAGDMLNLAPKEQQPRVRGWLL 317

Human   316 ASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPTLTKGATVADSL---DEQEAAF 377
            ||:|||||||:||||||:||:|:|||..|..::::.|:...|....:.|.:..|:   ...|...
Zfish   318 ASVDGQTTGLVPANYVKVLGRRRGRKHAELERMAQAQEPAQNLPAPQTALITASVPTTTHSEDLL 382

Human   378 ESVFVETNKVPV--------APDSIGKDGEKQDL 403
            |||:.||..:.:        :.|::....||.||
Zfish   383 ESVYGETQGLGLEVQASTHNSRDTLVMHSEKMDL 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX13	NP_002609.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..68		30/63 (48%)
		Peroxin-13_N	117..254	CDD:461167	110/144 (76%)
		Targeting to peroxisomes. /evidence=ECO:0000269|PubMed:11390669	145..233		64/95 (67%)
		Interaction with PEX19. /evidence=ECO:0000269|PubMed:11390669	175..196		18/20 (90%)
		SH3_PEX13_eumet	276..333	CDD:212798	47/56 (84%)
pex13	NP_956939.1	Peroxin-13_N	111..256	CDD:461167	110/144 (76%)
		SH3_PEX13_eumet	278..335	CDD:212798	47/56 (84%)