Protein Alignment PEX13 and Pex13

DIOPT Version :10

• Sequence 1: NP_002609.1
• Gene: PEX13 / 5194
• HGNCID: 8855
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_610850.1
• Gene: Pex13 / 36462
• FlyBaseID: FBgn0033812
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 426
• Identity: 131/426 - (30%)
• Similarity: 204/426 - (47%)
• Gaps: 81/426 - (19%)

Human    32 SADLGPTLMTRPGQP--ALTRVP------------PPILPR-PSQQTGSSSVNTFRPAYSSFSSG 81
            |:.:|..:.:..|.|  |:.|.|            ||.||: |.|||         ..|..|.||
  Fly    21 SSSIGVGVSSGGGYPPEAVLRTPYGNVRALPGPAQPPPLPQSPFQQT---------QQYGGFGSG 76

Human    82 YGA--YGNSFYGGYSPYSYGYNGL-------------------------------GYNRLRV--D 111
            ||.  ||...|||::..::||.||                               ||||...  :
  Fly    77 YGGNNYGLGGYGGFNSGAFGYGGLGGFGSGLGSGFGSGYGYGGGYGGGYGGGFGGGYNRFGAMGE 141

Human   112 DLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFSRLKIHFT 176
            :....||:..||.|||.|||||||:|.|..:::.|:|:||.|:.:||||:|.||.:|.||:..|.
  Fly   142 NDAEQRFIYMAESSSRPAFQSIESLVSAIGNIASMLDSTFFALTSSFRAILGVATNFVRLRSVFA 206

Human   177 KVFSAFALVRTIRYLYRRLQRMLGLRR----GSENEDLWAE--SEGTVACLGAEDRAATSAKSWP 235
            :.::.||:.|.:.::||::...|.|..    .:..:..:||  :|......||.:........||
  Fly   207 QFWTTFAIFRGLNWMYRKILYWLRLSNLDPSSAAFKKAFAEALNENNGQARGAPNVPRKGNSPWP 271

Human   236 IFLFFAVILGGPYLIWKLL----STHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRAG 296
            :..|.:.|...||||.|||    :|..:|..:...|.:    .:..:|.|:|.|.|..|:|.|||
  Fly   272 VLAFISFIFTAPYLIMKLLGTVTNTAQEEARNPAKWTA----PIQTQAVYEFVARSPSELSLRAG 332

Human   297 DMLNLALKEQQPKVR----GWLLASLDGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTN 357
            .||::|.::.|..:.    ||.||:.:|||:|:||.:||| ..::..::..:.:|.::.|....|
  Fly   333 QMLHVAPRDIQQTLNLLNTGWALATTNGQTSGIIPISYVK-SPQQMRQEMQDQTKPAQPQPELMN 396

Human   358 PTLTKGATVADSLDEQEAAFESVFVETNKVPVAPDS 393
              |:.||..:..| ||:..::.......:.|:.|.|
  Fly   397 --LSAGAFASPPL-EQQMNYDFNLAAQQQAPLGPPS 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX13	NP_002609.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..68		15/50 (30%)
		Peroxin-13_N	117..254	CDD:461167	53/142 (37%)
		Targeting to peroxisomes. /evidence=ECO:0000269|PubMed:11390669	145..233		28/93 (30%)
		Interaction with PEX19. /evidence=ECO:0000269|PubMed:11390669	175..196		6/20 (30%)
		SH3_PEX13_eumet	276..333	CDD:212798	26/60 (43%)
Pex13	NP_610850.1	Peroxin-13_N	147..290	CDD:461167	53/142 (37%)
		SH3_PEX13_eumet	312..373	CDD:212798	27/61 (44%)