Protein Alignment PEX13 and prx-13

DIOPT Version :10

• Sequence 1: NP_002609.1
• Gene: PEX13 / 5194
• HGNCID: 8855
• Length: 403
• Species: Homo sapiens
• Sequence 2: NP_495513.1
• Gene: prx-13 / 174192
• WormBaseID: WBGene00004198
• Length: 330
• Species: Caenorhabditis elegans
• Alignment Length: 351
• Identity: 135/351 - (38%)
• Similarity: 188/351 - (53%)
• Gaps: 42/351 - (11%)

Human    49 TRVPPPILPRP-SQQTGSSSVNT-FRPAYSSFSSGYGAY---GNSFYGGYSPY----SYGYNGLG 104
            |..|||:.||. ..|..:..:|| |     .:..|||..   |:..|||...|    .||..|.|
 Worm     6 TNQPPPLPPRSFDNQMSNPMINTGF-----GYGGGYGMNTFPGSGMYGGGGMYGGGMGYGGFGGG 65

Human   105 YNRLRVDDLPPSRFVQQAEESSRGAFQSIESIVHAFASVSMMMDATFSAVYNSFRAVLDVANHFS 169
            :|.:.....|.|.|.:.|||.||||||||||:|:|.:||:.|:::|.:|||:|||||:.|...|.
 Worm    66 FNHMGYGQGPDSNFARLAEEQSRGAFQSIESVVNAVSSVANMLNSTHNAVYSSFRAVIGVVEQFG 130

Human   170 RLKIHFTKVFSAFALVRTIRYLYRRLQRMLGLR---RGSENEDLWAESEG-TVACLGAEDRAATS 230
            |||...:.|..:.|:.|.:...:|.|..||.|:   ..|..|..|..|:. ....|||....|
 Worm   131 RLKTQLSSVVVSLAVFRWVYRFWRWLLVMLKLKPASYASAAEMAWGTSQPYATDVLGATRTPA-- 193

Human   231 AKSWPIFLFFAVILGGPYLIWKLLSTHSDEVTDSINWASGEDDHVVARAEYDFAAVSEEEISFRA 295
            :.:||..||:.|.:|||:||::.:|.......:...||:|...|..|:|.:||.|.:|:|:||..
 Worm   194 SVNWPAALFWVVAIGGPWLIYRCVSQMVQAAEEKRKWATGAAPHYTAQALFDFQASNEQELSFMN 258

Human   296 GDMLNLALKEQQPKVRGWLLASL-DGQTTGLIPANYVKILGKRKGRKTVESSKVSKQQQSFTNPT 359
            |:.|.:|.||:||:||||||||: ||...||:|.|||:|:|              ||.||   |.
 Worm   259 GETLRVAPKEEQPRVRGWLLASVADGSRIGLVPINYVRIVG--------------KQSQS---PP 306

Human   360 LTKGATVADSLDEQEAAFESVFVETN 385
            ||:    ..:||....||.:..:.:|
 Worm   307 LTQ----QSNLDTFVNAFPARDLNSN 328

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX13	NP_002609.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..68		7/19 (37%)
		Peroxin-13_N	117..254	CDD:461167	59/140 (42%)
		Targeting to peroxisomes. /evidence=ECO:0000269|PubMed:11390669	145..233		31/91 (34%)
		Interaction with PEX19. /evidence=ECO:0000269|PubMed:11390669	175..196		4/20 (20%)
		SH3_PEX13_eumet	276..333	CDD:212798	32/57 (56%)
prx-13	NP_495513.1	Peroxin-13_N	78..217	CDD:461167	59/140 (42%)
		SH3_PEX13_eumet	239..297	CDD:212798	32/57 (56%)