Protein Alignment PEX12 and pex12

DIOPT Version :10

• Sequence 1: NP_000277.1
• Gene: PEX12 / 5193
• HGNCID: 8854
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_956499.2
• Gene: pex12 / 393174
• ZFINID: ZDB-GENE-040426-929
• Length: 350
• Species: Danio rerio
• Alignment Length: 358
• Identity: 216/358 - (60%)
• Similarity: 272/358 - (75%)
• Gaps: 9/358 - (2%)

Human     1 MAEHGAHFTAASVADDQPSIFEVVAQDSLMTAVRPALQHVVKVLAESNPTHYGFLWRWFDEIFTL 65
            |||.|||.|.|:.|:|:||:|||:|||||||||:|||.|.||:||.|||..||.|||.||||:.:
Zfish     1 MAERGAHLTTAAPAEDRPSVFEVLAQDSLMTAVKPALLHAVKILATSNPARYGVLWRRFDEIYVI 65

Human    66 LDLLLQQHYLSRTSASFSENFYGLKRIVMGDTHKSQRLASAGLPKQQLWKSIMFLVLLPYLKVKL 130
            ||:|||.|:|||||||||||||||||:   .:| |.|.|..||.::|.|:|::.|.|:|||..||
Zfish    66 LDMLLQHHFLSRTSASFSENFYGLKRV---GSH-SARAAHLGLRRRQHWRSLLLLALIPYLHTKL 126

Human   131 EKLVSSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLVQQLRYILGKAQHHSPLLRL 195
            ||:::..|:||::||..|.|..::.|||||||||||.|||:||...|||.|:.||.:.|||||.|
Zfish   127 EKILARQRDEDDFSIRLPQSFLQKMYRAFLAAYPFVCMAWDGWVFCQQLLYVFGKTRTHSPLLWL 191

Human   196 AGVQLGRLTVQDIQALEHKPAKASMMQQPARSVSEKINSALKKAVGGVALSLSTGLSVGVFFLQF 260
            |||:|..||..||.:|:.||:...:  ...:|..||:...:..||||||:||||.||:|||||||
Zfish   192 AGVKLSYLTANDIHSLDLKPSGPEL--SSGQSFGEKLQRVVSTAVGGVAVSLSTSLSIGVFFLQF 254

Human   261 LDWWYSSENQETIKSLTALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKTRVNDTVLATSGYVFC 325
            |:||||||||.|:||||:|||||||:||.....|....|   |||:|||.|.|||.|||||||||
Zfish   255 LEWWYSSENQSTVKSLTSLPTPPPPLHLHSQETSHTHIK---VCPICRKVRTNDTALATSGYVFC 316

Human   326 YRCVFHYVRSHQACPITGYPTEVQHLIKLYSPE 358
            |||::.||:::..||:||||:|:|||||:|:|:
Zfish   317 YRCIYVYVKANHRCPLTGYPSELQHLIKIYTPD 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX12	NP_000277.1	Pex2_Pex12	26..267	CDD:398431	141/240 (59%)
		mRING_PEX12	302..355	CDD:438115	36/52 (69%)
pex12	NP_956499.2	Pex2_Pex12	26..261	CDD:398431	141/240 (59%)
		mRING_PEX12	294..346	CDD:438115	36/51 (71%)