Protein Alignment PEX12 and pex12

DIOPT Version :10

• Sequence 1: NP_000277.1
• Gene: PEX12 / 5193
• HGNCID: 8854
• Length: 359
• Species: Homo sapiens
• Sequence 2: XP_002933865.1
• Gene: pex12 / 100380099
• XenbaseID: XB-GENE-1014986
• Length: 353
• Species: Xenopus tropicalis
• Alignment Length: 358
• Identity: 232/358 - (64%)
• Similarity: 289/358 - (80%)
• Gaps: 6/358 - (1%)

Human     1 MAEHGAHFTAASVADDQPSIFEVVAQDSLMTAVRPALQHVVKVLAESNPTHYGFLWRWFDEIFTL 65
            |||.|||.|..|::||:|||||||||:|||.||||||.|:|||||||||..||.|||||||::||
 Frog     1 MAERGAHITTTSLSDDRPSIFEVVAQESLMAAVRPALHHIVKVLAESNPARYGTLWRWFDELYTL 65

Human    66 LDLLLQQHYLSRTSASFSENFYGLKRIVMGDTHKSQRLASAGLPKQQLWKSIMFLVLLPYLKVKL 130
            ||.|||||.||..|||||||||||||:.:|     ::.....||:::.|||::.|||:|||::||
 Frog    66 LDWLLQQHSLSWASASFSENFYGLKRVTLG-----RKGGQQNLPRKEYWKSLLLLVLVPYLRIKL 125

Human   131 EKLVSSLREEDEYSIHPPSSRWKRFYRAFLAAYPFVNMAWEGWFLVQQLRYILGKAQHHSPLLRL 195
            |||||.||||::|||..|:|..||.|:|.||:||||.:.||.|||..||:||||..:||||||.|
 Frog   126 EKLVSRLREEEDYSIQNPTSFHKRCYKAILASYPFVKLGWEAWFLFYQLKYILGNGKHHSPLLGL 190

Human   196 AGVQLGRLTVQDIQALEHKPAKASMMQQPARSVSEKINSALKKAVGGVALSLSTGLSVGVFFLQF 260
            |||||.|||::|::|:|.:....:.:.. |.|:|.:|...||||:|.||||:|:.||:|||||||
 Frog   191 AGVQLNRLTMEDLRAMEKQQEMTNTVSN-AVSISHRIRDILKKALGAVALSVSSSLSLGVFFLQF 254

Human   261 LDWWYSSENQETIKSLTALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKTRVNDTVLATSGYVFC 325
            ||||||:|||||:|||:.||.||||:|.|..:.||||||::||||||||.|||||.|.|||||||
 Frog   255 LDWWYSAENQETLKSLSNLPVPPPPIHFDLETYSPLLPKLRTVCPLCRKVRVNDTALGTSGYVFC 319

Human   326 YRCVFHYVRSHQACPITGYPTEVQHLIKLYSPE 358
            |||.::||::||.||::|||||:|||||||:|:
 Frog   320 YRCAYYYVKTHQRCPVSGYPTELQHLIKLYTPD 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX12	NP_000277.1	Pex2_Pex12	26..267	CDD:398431	148/240 (62%)
		mRING_PEX12	302..355	CDD:438115	40/52 (77%)
pex12	XP_002933865.1	Pex2_Pex12	26..260	CDD:398431	147/239 (62%)
		mRING_PEX12	296..349	CDD:438115	40/52 (77%)