Protein Alignment PEX10 and PEX10

DIOPT Version :10

• Sequence 1: NP_722540.1
• Gene: PEX10 / 5192
• HGNCID: 8851
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_010551.1
• Gene: PEX10 / 851858
• SGDID: S000002673
• Length: 337
• Species: Saccharomyces cerevisiae
• Alignment Length: 376
• Identity: 89/376 - (23%)
• Similarity: 147/376 - (39%)
• Gaps: 100/376 - (26%)

Human     6 ASPPEVIRAAQKDEYYRGGLRSAAGGALHSLAGARKWL-EWRKEVELLSDVAYFGLTTLAGYQTL 69
            |..|.:::|.||||..: ||.......|..|..::.:: .:.||:.:.:.:.|...||....:||
Yeast    23 ADAPSIVQAHQKDEQIQ-GLLIMKVTELCKLIKSQLFVNSYPKELSIFAKLLYLLFTTGRRGRTL 86

Human    70 GEEYVSIIQVDPSRIHVPSSLRRGVLVTLHAVLPYLLDKALLPLEQELQADPDSGRPLQGSLGPG 134
            |||||.:...:.....:...|:..|....:.:.||.:.|..
Yeast    87 GEEYVDLTYTNRKGTRLAGRLKMIVFAFAYPLCPYFITKLY------------------------ 127

Human   135 GRGCSGARRWMRHHTATLTEQQRRALLRAVFVLRQGLA-CLQRLHVAWFYIHGVFYHLAKRLTGI 198
                   ::.|:::..:..|.     ..:|....:||. .:..:|:..||..|.||.::||:.|:
Yeast   128 -------KKIMKNNKESKIED-----TESVAAFCKGLLDFILDVHMTLFYFKGAFYSISKRIFGM 180

Human   199 TYQALRPDPLRVLMSVAPSALQLRVRSLPGEDLRARVSYRLLGVISLLHLVL--------SMGLQ 255
            .|             |....|.....:...|..:   .|::||.|.|...|:        ::|..
Yeast   181 RY-------------VFKHILSKNEANFREEGSQ---KYKVLGYILLAQNVMKWYPVLTSTLGSW 229

Human   256 LYGFRQRQRARKEWRLHRGLSHRRASLEERA-------------------VSRNPL--------- 292
            :||       ||  |.:..::.....|:||:                   ..:|.|
Yeast   230 IYG-------RK--RTNDSITRSSVGLQERSEHESIEGIPKESQLTHINLSDKNQLPFIPEASRK 285

Human   293 CTLCLEERRHPTATPCGHLFCWECITAWCSSKAECPLCREKFPPQKLIYLR 343
            |.|||.....|:..||||||||.|:.:||..:.||||||:...||:::.||
Yeast   286 CILCLMNMSDPSCAPCGHLFCWSCLMSWCKERPECPLCRQHCQPQEILVLR 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX10	NP_722540.1	Pex2_Pex12	18..263	CDD:398431	50/254 (20%)
		RING-HC_PEX10	293..342	CDD:438190	24/48 (50%)
PEX10	NP_010551.1	PEX10	5..337	CDD:227861	77/351 (22%)