Protein Alignment PEX10 and pas4

DIOPT Version :10

• Sequence 1: NP_722540.1
• Gene: PEX10 / 5192
• HGNCID: 8851
• Length: 346
• Species: Homo sapiens
• Sequence 2: NP_595592.1
• Gene: pas4 / 2539774
• PomBaseID: SPBC17A3.10
• Length: 306
• Species: Schizosaccharomyces pombe
• Alignment Length: 305
• Identity: 69/305 - (22%)
• Similarity: 111/305 - (36%)
• Gaps: 120/305 - (39%)

Human    68 TLGEEYVSII---QVDPSRIHVPSSLRRGVLVTLHAVLPY----LLDKALLPLEQELQADPDSGR 125
            |.||...|:|   .:|...:||...|::....:... ||:    ||.:|::..|:.|....:|.:
pombe    93 TTGERMTSLIFSLVIDLVGVHVNKLLKQASYSSSFK-LPFGLRNLLPEAVISKEKHLVYILNSFK 156

Human   126 PLQGSLGPGGRGCSGARRWMRHHTATLTEQQRRALLRAVFVLRQGLACL-QRLHVAWFYIHGVFY 189
            |:                                ||:.|.::|  ..|| .:.|.|
pombe   157 PI--------------------------------LLKLVSIIR--FLCLTMKGHCA--------- 178

Human   190 HLAKRLTGITYQALRPDPLRVLMSVAPSALQLRVRSLPGEDLRARVSYRLLGVISLL--HLVLSM 252
            .:::.|.|:.|.:|                         :::......::|.::.||  .|:.|:
pombe   179 TVSQLLLGLKYISL-------------------------DEINPEEKKKVLTLLLLLGSRLIASI 218

Human   253 GLQLYGFRQRQRARKEWRLHRGLSHRRASLEERAVS----------RNPL---------CTLCLE 298
                                  |.|..:..::..:|          :|.|         |:||:|
pombe   219 ----------------------LQHSNSYFDQHTISSITDERDLEDKNKLPFIPEGNRKCSLCME 261

Human   299 ERRHPTATPCGHLFCWECITAWCSSKAECPLCREKFPPQKLIYLR 343
            ....|.||.|||:|||.||..|.|.|:||||||....|.|:|.||
pombe   262 FIHCPAATECGHIFCWSCINGWTSKKSECPLCRAFSSPSKIILLR 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX10	NP_722540.1	Pex2_Pex12	18..263	CDD:398431	35/204 (17%)
		RING-HC_PEX10	293..342	CDD:438190	27/48 (56%)
pas4	NP_595592.1	PEX10	1..306	CDD:227861	67/303 (22%)