Protein Alignment PEX7 and PEX7

DIOPT Version :10

• Sequence 1: NP_000279.1
• Gene: PEX7 / 5191
• HGNCID: 8860
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_010426.1
• Gene: PEX7 / 851720
• SGDID: S000002549
• Length: 375
• Species: Saccharomyces cerevisiae
• Alignment Length: 381
• Identity: 115/381 - (30%)
• Similarity: 180/381 - (47%)
• Gaps: 85/381 - (22%)

Human    11 MLR--TPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRL--FRSFDWNDGLF 71
            |||  ..|..||..::||:...|||.|...::|:.|.|.|.||:.|.:| |:  ..||...|.||
Yeast     1 MLRYHMQGFSGYGVQYSPFFDNRLAVAAGSNFGLVGNGKLFILEIDRSG-RIVEVNSFLTQDCLF 64

Human    72 DVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQT 136
            |:.|:|::|:.::...|||:|:|:||.....|:.::|||.:||:|.:|:.. ..|..:|.|||.:
Yeast    65 DLAWNESHENQVLVAQGDGTLRLFDTTFKEFPIAIFKEHEREVFSCNWNLV-NRQNFLSSSWDGS 128

Human   137 VKLWDPTVGKSLCT------------------------FRG---HESIIYSTIWSPHIPGCFASA 174
            :|:|.|...:||.|                        |.|   :.:.:|...:|||......|.
Yeast   129 IKIWSPLRKQSLMTLTPRPLEITKMVDPLNAIILKKKSFTGISKNRNCVYQAQFSPHDQNLVLSC 193

Human   175 SGDQTLRIWDVKAAGVRIVIPA---------HQA-EILSCDWCKYNENLLVTGAVDCSLRGWDLR 229
            ||:....::|::       :|:         |.. |.|:||:.||...::.||.||.::|.||:|
Yeast   194 SGNSYASLFDIR-------LPSGKNQNNFLVHSGLEALTCDFNKYRPYVVATGGVDNAIRIWDIR 251

Human   230 --------NVRQPVFELL-----------GHTYAIRRVKFSPFHASVLASCSYDFTVRFWNFSKP 275
                    .:::.|...|           .|..|||:|.:||.|:::|.|.|||.|.|.|.....
Yeast   252 MLNKNESATIKRTVPGQLHNSSCINEIPNAHGLAIRKVTWSPHHSNILMSASYDMTCRIWRDLSN 316

Human   276 DSLLETVE---------------HHTEFTCGLDFSL-QSPTQVADCSWDETIKIYD 315
            |...||.:               .|:||..|.|:|| ..|..||..:||..:.:::
Yeast   317 DGAKETYKTNSTDATKGSIFNFTQHSEFVFGADWSLWGKPGYVASTAWDGNLFVWN 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX7	NP_000279.1	WD40	<46..317	CDD:441893	101/344 (29%)
		WD 1	65..96		12/30 (40%)
		WD40 repeat	70..109	CDD:293791	14/38 (37%)
		WD 2	109..141		12/31 (39%)
		WD40 repeat	115..153	CDD:293791	14/61 (23%)
		WD 3	153..184		8/33 (24%)
		WD40 repeat	158..195	CDD:293791	8/36 (22%)
		WD 4	196..227		12/40 (30%)
		WD40 repeat	202..239	CDD:293791	14/44 (32%)
		WD 5	240..271		15/30 (50%)
		WD40 repeat	245..283	CDD:293791	17/37 (46%)
		WD 6	284..315		12/31 (39%)
PEX7	NP_010426.1	WD40 repeat	11..55	CDD:293791	16/45 (36%)
		WD40 repeat	65..102	CDD:293791	14/36 (39%)
		WD40	<71..372	CDD:475233	85/307 (28%)
		WD40 repeat	107..144	CDD:293791	14/63 (22%)
		WD40 repeat	152..214	CDD:293791	19/71 (27%)
		WD40 repeat	221..270	CDD:293791	19/59 (32%)
		WD40 repeat	286..339	CDD:293791	6/21 (29%)
		WD40 repeat	345..371	CDD:293791