Protein Alignment PEX7 and Pex7

DIOPT Version :10

• Sequence 1: NP_000279.1
• Gene: PEX7 / 5191
• HGNCID: 8860
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_648251.1
• Gene: Pex7 / 38994
• FlyBaseID: FBgn0035922
• Length: 339
• Species: Drosophila melanogaster
• Alignment Length: 327
• Identity: 141/327 - (43%)
• Similarity: 185/327 - (56%)
• Gaps: 20/327 - (6%)

Human    14 TPGRHGYAAEFSPYLPGRLACATAQHYGIAGCGTLLILD---------PDEAGLRLFRSFDWNDG 69
            |..||||:..|||:....|..||:|.||:||.|:|.:|:         .|...|......:|:||
  Fly     8 TTDRHGYSLRFSPFEANYLLLATSQLYGLAGGGSLFLLEQNSNTNSSSTDGQSLGELCRLEWSDG 72

Human    70 LFDVTWSENNEHVLITCSGDGSLQLW---DTAKAAG------PLQVYKEHAQEVYSVDWSQTRGE 125
            ||||.|......:..|.|||||||:|   |...|:.      ||...:||..||||:||.:....
  Fly    73 LFDVAWCPYAADIAATASGDGSLQIWCGLDGESASNQLTPKQPLICLQEHKNEVYSLDWGEKWNY 137

Human   126 QLVVSGSWDQTVKLWDPTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWD-VKAAG 189
            ..::|||||.|:||||.....|:.||.||..:||...:||.|...|||.|.|..|.:|: :..||
  Fly   138 HTLLSGSWDCTLKLWDCNRQNSITTFVGHNDLIYGAKFSPLIANLFASVSTDGHLNLWNSLDFAG 202

Human   190 VRIV-IPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPF 253
            ..:: |.||.:|.|.|||..::.|:||||..|..:||||||.:|..||||....:|:||:..||.
  Fly   203 KPLMSIEAHASEALCCDWSHFDRNVLVTGGSDGLIRGWDLRKMRTHVFELYSGEFAVRRLACSPH 267

Human   254 HASVLASCSYDFTVRFWNFSKPDSLLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYDPAC 318
            .|:||||.:||||.|.||..:.:|..|....||||.||||::.....|:|||.||....:|.|.|
  Fly   268 SAAVLASANYDFTTRIWNLERGESAQEVNARHTEFVCGLDWNPHRTHQLADCGWDSLANVYTPQC 332

Human   319 LT 320
            |:
  Fly   333 LS 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PEX7	NP_000279.1	WD40	<46..317	CDD:441893	122/290 (42%)
		WD 1	65..96		17/33 (52%)
		WD40 repeat	70..109	CDD:293791	18/47 (38%)
		WD 2	109..141		16/31 (52%)
		WD40 repeat	115..153	CDD:293791	17/37 (46%)
		WD 3	153..184		13/30 (43%)
		WD40 repeat	158..195	CDD:293791	14/38 (37%)
		WD 4	196..227		15/30 (50%)
		WD40 repeat	202..239	CDD:293791	20/36 (56%)
		WD 5	240..271		15/30 (50%)
		WD40 repeat	245..283	CDD:293791	18/37 (49%)
		WD 6	284..315		14/30 (47%)
Pex7	NP_648251.1	WD40	53..328	CDD:475233	118/274 (43%)
		WD40 repeat	74..121	CDD:293791	17/46 (37%)
		WD40 repeat	126..164	CDD:293791	17/37 (46%)
		WD40 repeat	171..209	CDD:293791	13/37 (35%)
		WD40 repeat	215..251	CDD:293791	18/35 (51%)
		WD40 repeat	259..296	CDD:293791	18/36 (50%)
		WD40 repeat	303..328	CDD:293791	10/24 (42%)