DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ATP5MC3 and Vha16-2

DIOPT Version :9

Sequence 1:	NP_001002258.1	Gene:	ATP5MC3 / 518	HGNCID:	843	Length:	142	Species:	Homo sapiens
Sequence 2:	NP_729707.1	Gene:	Vha16-2 / 39282	FlyBaseID:	FBgn0028668	Length:	158	Species:	Drosophila melanogaster

Alignment Length:	148	Identity:	37/148 - (25%)
Similarity:	60/148 - (40%)	Gaps:	25/148 - (16%)

- Green bases have known domain annotations that are detailed below.

Human     7 LACTPSLIRA---------GSRVAYRPISASVLSRPEASRTGEGSTVFNG--AQNG--VSQLIQR 58
            |.||.:.:..         |:.|:...|:...::||:.........|..|  |..|  ||.||
  Fly    16 LGCTGAAVAIIFTTLGASYGTAVSGVGIAKMAVNRPDMIMKAIIPVVMAGIIAIYGLVVSVLI-- 78

Human    59 EFQTSAISRDIDTAAKFIGAGAA-TVGVAG--SGAGIGTVFGSLIIGYARNPSLKQQLFSYAILG 120
               ..:|..|......::..||. :||:.|  :|..||....:.:.|.|..|    :||...:|.
  Fly    79 ---AGSIGDDYTMEDSYVHLGAGLSVGLPGLTAGVAIGIAGDAGVRGTAEQP----RLFVGMVLI 136

Human   121 FALSEAMGLFCLMVAFLI 138
            ...:|.:.|:.|:||..:
  Fly   137 LIFAEVLALYGLIVAIYL 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ATP5MC3	NP_001002258.1	ATP9	68..142	CDD:164765	20/74 (27%)
Vha16-2	NP_729707.1	PRK06558	14..158	CDD:235830	37/148 (25%)
		ATP-synt_C	15..120	CDD:294318	26/108 (24%)
		ATP-synt_C	94..154	CDD:278563	19/63 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810