Protein Alignment RAB23 and Rab8

DIOPT Version :10

• Sequence 1: NP_057361.3
• Gene: RAB23 / 51715
• HGNCID: 14263
• Length: 237
• Species: Homo sapiens
• Sequence 2: NP_524172.1
• Gene: Rab8 / 40168
• FlyBaseID: FBgn0262518
• Length: 207
• Species: Drosophila melanogaster
• Alignment Length: 227
• Identity: 70/227 - (30%)
• Similarity: 112/227 - (49%)
• Gaps: 31/227 - (13%)

Human    11 KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDEDVRLMLWDTAGQEEFDAIT 75
            |::::|:..|||:.::.|:.:..|...:..|||:||..|.|:::::.::|.:|||||||.|..||
  Fly    10 KLLLIGDSGVGKTCILFRFSEDAFNTTFISTIGIDFKIRTIELDNKKIKLQIWDTAGQERFRTIT 74

Human    76 KAYYRGAQACVLVFSTTDRESFEAVSSWREKVVAEV-GDIPTVLVQNKIDLLDDSCIKNEEAEAL 139
            .||||||...:||:..|..:|||.:.:|...:.... .|:..:|:.||.:|.|...:..|..|.|
  Fly    75 TAYYRGAMGIMLVYDITQEKSFENIKNWIRNIEENASADVEKMLLGNKCELTDKRQVSKERGEQL 139

Human   140 AKRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQKLKQQIAEDPELTHSSSNKIGVFNTSGGSHSGQ 204
            |....::|..||.|..:||.|.|..||.....|.::::..:              |...|.|
  Fly   140 AIEYGIKFMETSAKASINVEEAFLTLASDIKAKTEKRMEAN--------------NPPKGGH--- 187

Human   205 NSGTLNGGDVINLRPNKQRTKKNRNPFSSCSI 236
                       .|:|...|||.:.  .|.||:
  Fly   188 -----------QLKPMDSRTKDSW--LSRCSL 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB23	NP_057361.3	Rab23_like	10..169	CDD:133306	58/158 (37%)
Rab8	NP_524172.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	58/161 (36%)