Protein Alignment RAB23 and Rab27

DIOPT Version :10

• Sequence 1: NP_057361.3
• Gene: RAB23 / 51715
• HGNCID: 14263
• Length: 237
• Species: Homo sapiens
• Sequence 2: NP_726743.1
• Gene: Rab27 / 31103
• FlyBaseID: FBgn0025382
• Length: 236
• Species: Drosophila melanogaster
• Alignment Length: 172
• Identity: 54/172 - (31%)
• Similarity: 93/172 - (54%)
• Gaps: 10/172 - (5%)

Human    11 KMVVVGNGAVGKSSMIQRYCKGIFTKDYKKTIGVDFLERQIQVNDED----VRLMLWDTAGQEEF 71
            :.:|:|:..|||:.::.:|..|.|...:..|:|:||.|:::..|...    :.|.:|||||||.|
  Fly    19 QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSRGRRHRIHLQIWDTAGQERF 83

Human    72 DAITKAYYRGAQACVLVFSTTDRESFEAVSSW----REKVVAEVGDIPTVLVQNKIDLLDDSCIK 132
            .::|.|:||.|...:|:|..|..:||...::|    |....:|..|:  ||..||.|||....:.
  Fly    84 RSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDV--VLCGNKCDLLQLRVVS 146

Human   133 NEEAEALAKRLKLRFYRTSVKEDLNVNEVFKYLAEKYLQKLK 174
            .::..||.:|.:|.:..||.....||.|..:.|..:.:::::
  Fly   147 RDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIE 188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB23	NP_057361.3	Rab23_like	10..169	CDD:133306	54/165 (33%)
Rab27	NP_726743.1	P-loop containing Nucleoside Triphosphate Hydrolases	19..187	CDD:476819	54/169 (32%)