Protein Alignment CYB5R1 and CG11257

DIOPT Version :10

• Sequence 1: NP_057327.2
• Gene: CYB5R1 / 51706
• HGNCID: 13397
• Length: 305
• Species: Homo sapiens
• Sequence 2: NP_611419.1
• Gene: CG11257 / 37227
• FlyBaseID: FBgn0034442
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 317
• Identity: 78/317 - (24%)
• Similarity: 121/317 - (38%)
• Gaps: 97/317 - (30%)

Human     7 PVLLASLG--VGLVTLLGLAVGSYLVRRSRRPQVTL-------LDPNEKYLLRLLDKT---TVSH 59
            |..||.:|  .|.:.|:       .|:....|..|.       ||.:     ||.|:|   .|.|
  Fly   247 PPKLAKIGSETGKIELV-------FVKEEAEPWPTYGTHVSNRLDSS-----RLHDETFEYEVVH 299

Human    60 ----NTKRFRFALPTAHH--TLGLPVGKHIYLSTRIDGSLVIRPYTPVTSDEDQGYVDL------ 112
                |...|...|.:...  .:.||.|.|:.:...::|.::.|.||||    |..|:.|
  Fly   300 SKDFNHDSFELCLQSVGQKVLMVLPAGYHVDIEVPLEGRVIQRSYTPV----DHTYLRLENIRSS 360

Human   113 -------VIKVYLKGVHPKFPEGGKMSQYLDSLKVGDVVEFRGPSGLLTYTG-KGHFNIQPNKKS 169
                   :||.|         ..|.:|.:|..|:.|..|.:..|.|....:. ..|.||.
  Fly   361 RSECLHFLIKRY---------PNGPVSSHLQKLETGSRVHWSAPRGSFQLSDLTAHRNIL----- 411

Human   170 PPEPRVAKKLGMIAGGTGITPMLQLIRAILKVPEDPTQCF-LLFANQTEKDIILREDLEELQ--- 230
                       ::|.|:|:||:|.||:.|||...:..:.. ||:.|:|.:||.|:|.|.||.
  Fly   412 -----------LLAAGSGLTPILSLIQPILKRNTNRIESLQLLYFNKTNEDIWLKEKLHELHTDD 465

Human   231 -----ARYPNRFKLWFTLDHPPKDWAYSKGFVTADMIRE--HLPAPGDDVLVLLCGP 280
                 ..|.::.:     |:|.:        :..:::..  ....|.....||:|||
  Fly   466 ERFSCTNYVSQSE-----DNPQR--------IALELLAPLFQKNQPERCTYVLICGP 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CYB5R1	NP_057327.2	PLN02252	<38..300	CDD:215141	70/284 (25%)
CG11257	NP_611419.1	Cyt-b5	91..163	CDD:459698
		p23_NCB5OR	190..276	CDD:107240	9/35 (26%)
		cyt_b5_reduct_like	295..533	CDD:99780	63/257 (25%)