| Sequence 1: | NP_057315.3 | Gene: | NLK / 51701 | HGNCID: | 29858 | Length: | 527 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_477163.1 | Gene: | p38a / 42866 | FlyBaseID: | FBgn0015765 | Length: | 366 | Species: | Drosophila melanogaster |
| Alignment Length: | 10 | Identity: | 4/10 - (40%) |
|---|---|---|---|
| Similarity: | 5/10 - (50%) | Gaps: | 0/10 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 360 DPGDFSDIQW 369 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| NLK | NP_057315.3 | Required for interaction with TAB2. /evidence=ECO:0000250|UniProtKB:O54949 | 1..304 | ||
| Sufficient for interaction with DAPK3. /evidence=ECO:0000269|PubMed:21454679 | 1..125 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 22..72 | ||||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 90..140 | ||||
| Sufficient for interaction with DAPK3. /evidence=ECO:0000269|PubMed:21454679 | 124..416 | 4/10 (40%) | |||
| STKc_NLK | 137..508 | CDD:173748 | 4/10 (40%) | ||
| TQE | 298..300 | ||||
| Required for homodimerization and kinase activation and localization to the nucleus. /evidence=ECO:0000250|UniProtKB:O54949 | 428..527 | ||||
| Required for interaction with TAB2. /evidence=ECO:0000250|UniProtKB:O54949 | 434..527 | ||||
| p38a | NP_477163.1 | STKc_p38 | 9..354 | CDD:143356 | 2/4 (50%) |
| Blue background indicates that the domain is not in the aligned region. | |||||