Protein Alignment RASD1 and Rgk2

DIOPT Version :10

• Sequence 1: NP_057168.1
• Gene: RASD1 / 51655
• HGNCID: 15828
• Length: 281
• Species: Homo sapiens
• Sequence 2: NP_001286577.1
• Gene: Rgk2 / 37132
• FlyBaseID: FBgn0085419
• Length: 742
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 58/244 - (23%)
• Similarity: 111/244 - (45%)
• Gaps: 41/244 - (16%)

Human    12 PSDSE-LSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTI---EDFHRKFYSIRGEVY 72
            |.||| |..|....||:|:||.:.|||||:|::|:|..:...|..::   ::|..|..|:..:..
  Fly   513 PDDSENLDPPPPARYRVVMLGDAGVGKTALVNQFMTSEYMHTYDASLVLDDEFGEKTVSVLLDDE 577

Human    73 QLDILDTSGNHPFPAM---RRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKE 134
            :.|::..  :||...|   ..||.......::|||:.:|.||    |:.::|:: ....:|.||
  Fly   578 ESDMVFI--DHPSVEMSVENSLSTYEPHGCVVVFSVVDRSSF----RVAEEIIN-YLWQENYTK- 634

Human   135 NVDVPLVICGNKGDRDFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPS 199
              |..:::.|||.|....|.:..:|.:.|...  :...:.|.|:....::|::...:....:|..
  Fly   635 --DKAVILVGNKADLARARLITSQEGKALAAS--RDAKFIETSSGIQHNVDELLVGILKQMRLKE 695

Human   200 E--------------------MSPDLHRKVSVQYCDVLHKKALRNKKLL 228
            :                    ::.:|.:|:.:.  |:...|:..|..:|
  Fly   696 KREKKATASKMKTSRTHISLHLAKELLQKICLS--DISKSKSCENLHVL 742

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RASD1	NP_057168.1	Rhes_like	25..281	CDD:133343	52/230 (23%)
		Effector region	53..61		1/10 (10%)
Rgk2	NP_001286577.1	RGK	527..742	CDD:206715	51/228 (22%)