Protein Alignment RBMX2 and snRNP-U1-70K

DIOPT Version :10

• Sequence 1: NP_057108.2
• Gene: RBMX2 / 51634
• HGNCID: 24282
• Length: 322
• Species: Homo sapiens
• Sequence 2: NP_477205.1
• Gene: snRNP-U1-70K / 33982
• FlyBaseID: FBgn0016978
• Length: 448
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 86/346 - (24%)
• Similarity: 143/346 - (41%)
• Gaps: 72/346 - (20%)

Human     3 PLTK-VKLINELNEREVQLGVADKVSWHSEYKDSAW---------------IFLGGLPYELTEGD 51
            ||.| |:...|..||. :...|::|::..|.:.:.|               :|:..:.|:.:|..
  Fly    54 PLPKTVETRQERLERR-RREKAEQVAYKLEREIALWDPTEIKNATEDPFRTLFIARINYDTSESK 117

Human    52 IICVFSQYGEIVNINLVRDKKTGKSKGFCFLCYEDQRSTILAVDNFNGIKIKGRTIRVDHVSNYR 116
            :...|..||.|..|.|:.|:::||.||:.|:.||.:|....|..:.:|.||..:.:.|
  Fly   118 LRREFEFYGPIKKIVLIHDQESGKPKGYAFIEYEHERDMHAAYKHADGKKIDSKRVLV------- 175

Human   117 APKDSEEIDDVTRQLQEKGCGARTPSPSLSESSEDEKPTK-KH---KKDKKEKKKKKKEKEKADR 177
                     ||.|....||...|.....|..:........ ||   :.:::|:::.:.|:|:.||
  Fly   176 ---------DVERARTVKGWLPRRLGGGLGGTRRGGNDVNIKHSGREDNERERERYRLEREREDR 231

Human   178 EVQAEQPSSSS----PRRKTVKEKDDTGPKKHSSKNSERAQKSEPREGQKLPKSRTAYSGGAEDL 238
            |.......|:.    |.|       ..|.::..|::.||..:...|     .:...|.:|.:...
  Fly   232 EGPGRGGGSNGLDARPGR-------GFGAERRRSRSRERRDRERDR-----GRGAVASNGRSRSR 284

Human   239 ERELKKEK--PKHEHKSSSRREARE-EKTRIRDRGRSSDAHSSWYNGRSEGRSYRSRSRSRDKS- 299
            .||.:|.:  .:..:....||:.|: |:.|.|||.|             |.:..||:||.|:.|
  Fly   285 SRERRKRRAGSRERYDEFDRRDRRDRERERDRDRER-------------EKKKKRSKSRERESSR 336

Human   300 --HRHKRARRSRERESSNPSD 318
              ...||.||.|||.:.:..|
  Fly   337 ERRERKRERRDRERGTGSGGD 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RBMX2	NP_057108.2	RRM_ist3_like	27..115	CDD:409845	25/102 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	134..322		49/199 (25%)
snRNP-U1-70K	NP_477205.1	U1snRNP70_N	3..92	CDD:432406	11/38 (29%)
		RRM_snRNP70	101..188	CDD:409682	28/102 (27%)