Protein Alignment SLC25A39 and Shawn

DIOPT Version :10

• Sequence 1: XP_011523182.1
• Gene: SLC25A39 / 51629
• HGNCID: 24279
• Length: 365
• Species: Homo sapiens
• Sequence 2: NP_001027071.1
• Gene: Shawn / 3772641
• FlyBaseID: FBgn0031039
• Length: 387
• Species: Drosophila melanogaster
• Alignment Length: 383
• Identity: 149/383 - (38%)
• Similarity: 205/383 - (53%)
• Gaps: 75/383 - (19%)

Human     9 ISPLQQMVASGTGAVVTSLFMTPLDVVKVRLQSQRPSMASELMPSSRLWSLSYTKLPSSLQSTGK 73
            |.||||:.::.|||:||:.|||||||:|.|||:|:.::.|                       .|
  Fly    37 IRPLQQVASACTGAMVTACFMTPLDVIKTRLQAQQQALLS-----------------------NK 78

Human    74 CLLYCNGVLEPLYLCPNGARCATWFQDPT------RFTGTMDAFVKIVRHEGTRTLWSGLPATLV 132
            |.|||||:::  ::||    |.....:|.      ||:||:|||:||.|.||..:|||||..||:
  Fly    79 CFLYCNGLMD--HICP----CGPDTPNPAAAKPAPRFSGTIDAFIKISRTEGIGSLWSGLSPTLI 137

Human   133 MTVPATAIYFTAYDQLKAFLCGRALTSDLY---------------------APMVAGALARLGTV 176
            ..:|:|.|||.||:|.||..      :|::                     .|::||...|:..|
  Fly   138 SALPSTIIYFVAYEQFKARF------TDIHYKYTRRPDTIAHDIPHPIPFLVPLLAGVSGRILAV 196

Human   177 TVISPLELMRTKLQAQHVSYRELGACVRTAVAQGGWRSLWLGWGPTALRDVPFSVHPPPQALYWF 241
            |.:||:||:|||:|:|.:::.|:...:|..|...|...||.|..||.|||||||      .:||.
  Fly   197 TCVSPVELIRTKMQSQRMTHAEMFGTIRQVVQSQGVLGLWRGLPPTILRDVPFS------GIYWT 255

Human   242 NYELVKSWLNGFRPKDQTSVGMSFVAGGISGTVAAVLTLPFDVVKTQRQVALGAMEAVRVNP--- 303
            .||.:||......|    :...||.||.|||:|||.:|.|||||||..|:..|.......||
  Fly   256 CYEYLKSSFGVVEP----TFSFSFAAGAISGSVAATITTPFDVVKTHEQIEFGEKFIFSDNPPKQ 316

Human   304 LHVDSTWLLLRRIRAESGTKGLFAGFLPRIIKAAPSCAIMISTYEFGKSFFQRLNQDR 361
            :...|..:.|..|....|...:|:|..||:.|.||:||||||::|:|||||...|.|:
  Fly   317 VATKSVAMRLASIYRMGGVPAIFSGLGPRLFKVAPACAIMISSFEYGKSFFYHYNIDQ 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC25A39	XP_011523182.1	Mito_carr	9..152	CDD:395101	63/148 (43%)
		Mito_carr	161..252	CDD:395101	37/111 (33%)
		Mito_carr	257..356	CDD:395101	45/101 (45%)
Shawn	NP_001027071.1	Mito_carr	39..159	CDD:395101	62/154 (40%)
		Mito_carr	178..265	CDD:395101	37/92 (40%)
		Mito_carr	268..371	CDD:395101	46/106 (43%)