Protein Alignment PDHB and Pdhb

DIOPT Version :10

• Sequence 1: NP_000916.2
• Gene: PDHB / 5162
• HGNCID: 8808
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_651668.1
• Gene: Pdhb / 43437
• FlyBaseID: FBgn0039635
• Length: 365
• Species: Drosophila melanogaster
• Alignment Length: 353
• Identity: 237/353 - (67%)
• Similarity: 285/353 - (80%)
• Gaps: 2/353 - (0%)

Human     7 LVRRPLREVSGLLKRRFHWT--APAALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKV 69
            ::|..|.:.:...:|.|..:  |.||.|:|||||:|..:|:||.||::||:||||||||||||||
  Fly     1 MLRTRLIQAASSAQRAFSTSQKALAAKQMTVRDALNSALDDELARDDRVFILGEEVAQYDGAYKV 65

Human    70 SRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMS 134
            ||||||||||||:|||||:||||||||||||||||||:|||||:||||||||.:|||||||:|||
  Fly    66 SRGLWKKYGDKRVIDTPITEMGFAGIAVGAAMAGLRPVCEFMTWNFSMQAIDHIINSAAKTFYMS 130

Human   135 GGLQPVPIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVV 199
            .|...|||||||||||::||||||||||||||.|||||||:||:::|||:||:||||||.:|||.
  Fly   131 AGAVNVPIVFRGPNGAASGVAAQHSQCFAAWYAHCPGLKVLSPYDAEDARGLLKSAIRDPDPVVF 195

Human   200 LENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECE 264
            |||||:||..|........||||:||||||:.|.|..||:|:||:.|...|.|||.|:|:|:|.|
  Fly   196 LENELVYGTAFPVADNVADKDFLVPIGKAKVMRPGKDITLVAHSKAVETSLLAAAELAKKGIEAE 260

Human   265 VINMRTIRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGAD 329
            |||:|:|||:|..||.|||.||:||||||.||||.||||||||||||...|..||||..|..|.|
  Fly   261 VINLRSIRPLDTATIFASVRKTHHLVTVENGWPQHGVGAEICARIMEDQTFFELDAPVWRCAGVD 325

Human   330 VPMPYAKILEDNSIPQVKDIIFAIKKTL 357
            |||||||.||.:::|:|:|::.|..|.|
  Fly   326 VPMPYAKTLEAHALPRVQDLVEATLKVL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PDHB	NP_000916.2	PRK11892	<32..355	CDD:237011	228/322 (71%)
Pdhb	NP_651668.1	PLN02683	2..352	CDD:215368	235/349 (67%)