Protein Alignment PDHB and pdhb-1

DIOPT Version :10

• Sequence 1: NP_000916.2
• Gene: PDHB / 5162
• HGNCID: 8808
• Length: 359
• Species: Homo sapiens
• Sequence 2: NP_500340.1
• Gene: pdhb-1 / 177108
• WormBaseID: WBGene00015413
• Length: 352
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 231/349 - (66%)
• Similarity: 282/349 - (80%)
• Gaps: 1/349 - (0%)

Human    12 LREVSGLLKRRFHWTAP-AALQVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWK 75
            ||:...|...|...|:. ||..:|||||:||.||||::||::|||:||||||||||||:|:||||
 Worm     3 LRKCGNLFVARLAGTSTRAASTMTVRDALNQAMDEEIKRDDRVFLMGEEVAQYDGAYKISKGLWK 67

Human    76 KYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFNFSMQAIDQVINSAAKTYYMSGGLQPV 140
            |:||||::||||:||||||||||||.|||||||||||||||||||||:|||||||||||.|..||
 Worm    68 KHGDKRVVDTPITEMGFAGIAVGAAFAGLRPICEFMTFNFSMQAIDQIINSAAKTYYMSAGRVPV 132

Human   141 PIVFRGPNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELM 205
            ||||||||||:|||||||||.|:|||.||||||||.|:::||||||:|:||||:||||.||||::
 Worm   133 PIVFRGPNGAAAGVAAQHSQDFSAWYAHCPGLKVVCPYSAEDAKGLLKAAIRDDNPVVFLENEIL 197

Human   206 YGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRT 270
            ||..|....|..|.||::|||||||||.|.|:|:||:||.|...||||..|...||..||||:|:
 Worm   198 YGQSFPVGDEVLSDDFVVPIGKAKIERAGDHVTIVSYSRGVEFSLEAAKQLEAIGVSAEVINLRS 262

Human   271 IRPMDMETIEASVMKTNHLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYA 335
            :||.|.|:|..||.||:|||:||.|||..|:|:||.|::||...|:.||||.:||||.||||||.
 Worm   263 LRPFDFESIRQSVHKTHHLVSVETGWPFAGIGSEIAAQVMESDVFDQLDAPLLRVTGVDVPMPYT 327

Human   336 KILEDNSIPQVKDIIFAIKKTLNI 359
            :.||..::|..:.::.|:||:|||
 Worm   328 QTLEAAALPTAEHVVKAVKKSLNI 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PDHB	NP_000916.2	PRK11892	<32..355	CDD:237011	219/322 (68%)
pdhb-1	NP_500340.1	PRK11892	<15..347	CDD:237011	222/331 (67%)