Sequence 1: | NP_002600.1 | Gene: | PDGFRB / 5159 | HGNCID: | 8804 | Length: | 1106 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_523928.1 | Gene: | Tie / 38559 | FlyBaseID: | FBgn0014073 | Length: | 1233 | Species: | Drosophila melanogaster |
Alignment Length: | 943 | Identity: | 213/943 - (22%) |
---|---|---|---|
Similarity: | 323/943 - (34%) | Gaps: | 343/943 - (36%) |
- Green bases have known domain annotations that are detailed below.
Human 248 TYPRKESGRLVEPVTDFLLDMPYHIRSILHIPSA---------------ELEDSGTYTCNVTESV 297
Human 298 ND-HQDEKAINITVVESGYVRLLGEVGTLQFAELHRSRTLQVVFEAYPPP---TVLWFKDNRTLG 358
Human 359 DSSA---GEIALSTRNVSETRYVSELTLVRVKVAEAGHYTMRAFHEDAEVQLSFQLQINVPVRVL 420
Human 421 ELSESHP-----------------------DSGEQTVRCRGRGMPQ------PNIIWSACRDLKR 456
Human 457 C---PR-ELPPTLLGNSSEEESQLETNVTYWEEEQEFEVVSTLRLQHVDRPLSVRCTLRN----- 512
Human 513 -AVGQDTQEV---IVVPHSLPFKVVVISAILA-------------LVVLTIISLIIL----IMLW 556
Human 557 QKKPRYEIRWKVIES------------------------VSSD---------------------- 575
Human 576 GHEYIYVDPMQLPY-------------DST------WELPRDQLVLGRTLGSGAFGQVVEATAHG 621
Human 622 LS-HSQATMKVAVKMLKSTARSSEKQALMSELKIMSHLGPHLNVVNLLGACTKGGPIYIITEYCR 685
Human 686 YGDLVDYLHRNKHTFLQHHSDKRRPPSAELYSNALPVGLPLPSHVSLTGESDGGYMDMSKDESVD 750
Human 751 YVPMLDMKGDVKYADIESSNYMAPYDNYVPSAPERTCRATLINESPVLSYMDLVGFSYQVANGME 815
Human 816 FLASKNCVHRDLAARNVLICEGKLVKICDFGL-----------------ARDIMRDSNYISK--- 860
Human 861 GSTF-----------------------------------------LPLKWMAPESIFNSLYTTLS 884
Human 885 DVWSFGILLWEIFTLGGTPYPELPMNEQFYNAIKRGYRMAQPAHASDEIYEIMQKCWEEKFEIRP 949
Human 950 PFSQLVLLLERLLGEGYKKKYQQVDEEFLRSDH 982 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
PDGFRB | NP_002600.1 | ig | 37..114 | CDD:278476 | |
IG | 40..110 | CDD:214652 | |||
IG_like | 222..310 | CDD:214653 | 17/77 (22%) | ||
Ig1_PDGFR-alphabeta | 228..312 | CDD:143269 | 18/79 (23%) | ||
Ig4_PDGFR-alpha | 314..415 | CDD:143267 | 17/106 (16%) | ||
Ig | 425..523 | CDD:299845 | 23/139 (17%) | ||
PTKc_PDGFR_beta | 562..953 | CDD:133238 | 133/517 (26%) | ||
Pkinase_Tyr | 600..953 | CDD:285015 | 122/414 (29%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1019..1106 | ||||
Tie | NP_523928.1 | TyrKc | 854..1183 | CDD:197581 | 122/414 (29%) |
PTKc | 860..1187 | CDD:270623 | 122/412 (30%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR24416 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.910 |