DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PDGFRL and Cad96Ca

DIOPT Version :9

Sequence 1:	NP_001359002.1	Gene:	PDGFRL / 5157	HGNCID:	8805	Length:	375	Species:	Homo sapiens
Sequence 2:	NP_651349.1	Gene:	Cad96Ca / 43026	FlyBaseID:	FBgn0022800	Length:	773	Species:	Drosophila melanogaster

Alignment Length:	159	Identity:	30/159 - (18%)
Similarity:	54/159 - (33%)	Gaps:	43/159 - (27%)

- Green bases have known domain annotations that are detailed below.

Human    19 VTGQHLPKNKRPKEPGENRIKPTNK-KVKPKIPKMKDR---DSANSAPKTQSIMMQVLDKGRFQK 79
            |.|:...:.::|.|    .:.||.. ::....||.:.:   .:||::.:.:|.:
  Fly   238 VRGEQSGEEEQPDE----EVTPTTPVRISSTTPKSRTKLTPITANNSTRVESAI----------- 287

Human    80 PAATLSLLAGQTVELRCKGSRIGWSYPAYLDTFKDSRLSVKQNERYGQLTLVNSTSADTGEFSCW 144
            ||.|.:...|.         ....|.|..:.:.|.           |.:.:|    ...|.|...
  Fly   288 PAETTTPSGGH---------HNNSSSPITIFSLKS-----------GTIPIV----VTVGGFFVA 328

Human   145 VQLCSGYICRKDEAKTGSTYIFFTEKGEL 173
            :.:...|:||:.......|.....||.||
  Fly   329 IAVLLAYLCRRRLCAISRTLKKTKEKEEL 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PDGFRL	NP_001359002.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	22..64		8/45 (18%)
		IG_like	83..145	CDD:214653	9/61 (15%)
		Ig	293..372	CDD:386229
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568
		PTKc	474..742	CDD:270623
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900