Protein Alignment RAB14 and RabX6

DIOPT Version :10

• Sequence 1: NP_057406.2
• Gene: RAB14 / 51552
• HGNCID: 16524
• Length: 215
• Species: Homo sapiens
• Sequence 2: NP_001261219.1
• Gene: RabX6 / 38084
• FlyBaseID: FBgn0035155
• Length: 222
• Species: Drosophila melanogaster
• Alignment Length: 212
• Identity: 69/212 - (32%)
• Similarity: 110/212 - (51%)
• Gaps: 17/212 - (8%)

Human    13 KYIIIGDMGVGKSCLLHQFTEKKFMADCPH--TIGVEFGTRIIEVSGQKIKLQIWDTAGQERFRA 75
            |.|:.||.|||||.|..:|....|:.|...  |:|::...|...|:.::||||:|||.|.||..:
  Fly    10 KVILCGDYGVGKSSLFRRFATNTFITDTDRKSTLGLDHIDREYSVNEKQIKLQLWDTGGMERVAS 74

Human    76 VTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQR-DVTYEEA 139
            ||.|||:.|.||::|:.:...::::.||..|.|...... |..|.:.|||:||:.:. :|:.||.
  Fly    75 VTSSYYKFAEGAILVFALDNAASFHSLSQHLLDIVTYAE-NAKIFICGNKSDLDGREPEVSDEEV 138

Human   140 KQFAEENGLLF---LEASAKTGENVEDAFLEAAKKIYQNIQDGSLDLNAAESGVQHKP---SAPQ 198
            :.|.|:...|.   .:.|.::|..||:.|.:.::::. :.....::|.|.|    ||.   ....
  Fly   139 EAFCEQCHSLISATYKTSCRSGAGVEEMFRDISRQLV-HANRSKMELQALE----HKSFQVDTAS 198

Human   199 GGRLTSEPQPQREGCGC 215
            .|..|:|  .....|||
  Fly   199 SGAATNE--EDASSCGC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB14	NP_057406.2	Rab14	10..175	CDD:133322	58/167 (35%)
		Switch 1. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	42..47		2/6 (33%)
		Switch 2. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	68..77		3/8 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..215		6/29 (21%)
RabX6	NP_001261219.1	Rab	10..172	CDD:206640	58/162 (36%)