Protein Alignment RAB14 and Rab30

DIOPT Version :10

• Sequence 1: NP_057406.2
• Gene: RAB14 / 51552
• HGNCID: 16524
• Length: 215
• Species: Homo sapiens
• Sequence 2: NP_609094.1
• Gene: Rab30 / 33988
• FlyBaseID: FBgn0031882
• Length: 223
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 88/210 - (41%)
• Similarity: 134/210 - (63%)
• Gaps: 4/210 - (1%)

Human     7 NYSYIFKYIIIGDMGVGKSCLLHQFTEKKFMADCPHTIGVEFGTRIIEVSGQKIKLQIWDTAGQE 71
            :|.::||.:::|:.||||:||:.:||:..|......||||:|..:.:||.|:|||||||||||||
  Fly     3 DYKFLFKIVLVGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEVEGEKIKLQIWDTAGQE 67

Human    72 RFRAVTRSYYRGAAGALMVYDITRRSTYNHLSSWLTDARNLTNPNTVIILIGNKADLEAQRDVTY 136
            |||::|:||||.|...::||||:.:.|::.|..||.:.:...|...:.||:|||.|.: .|::..
  Fly    68 RFRSITQSYYRSAHALILVYDISCQPTFDCLPDWLREIQEYANSKVLKILVGNKTDRD-DREIPT 131

Human   137 EEAKQFAEENGLLFLEASAKTGENVEDAFLE-AAKKIYQ-NIQDGSLDLNAAESGVQHKPSAPQG 199
            :..::||:::.:.|||.|||..||||..|.| ||:.|.| ..:|||....||.:..|.:.|:...
  Fly   132 QIGEEFAKQHDMYFLETSAKEAENVERLFYEIAAELIGQARSKDGSSSAAAAAAQRQSEGSSIGL 196

Human   200 GRLTSEPQPQREGCG 214
            |..::: ..|...||
  Fly   197 GSFSAK-AAQSNCCG 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RAB14	NP_057406.2	Rab14	10..175	CDD:133322	76/166 (46%)
		Switch 1. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	42..47		3/4 (75%)
		Switch 2. /evidence=ECO:0000269|PubMed:26032412, ECO:0007744|PDB:4D0G	68..77		7/8 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	188..215		6/27 (22%)
Rab30	NP_609094.1	Rab30	1..168	CDD:133314	75/165 (45%)