Protein Alignment VPS54 and vps54

DIOPT Version :10

• Sequence 1: NP_057600.2
• Gene: VPS54 / 51542
• HGNCID: 18652
• Length: 977
• Species: Homo sapiens
• Sequence 2: XP_002939365.2
• Gene: vps54 / 100380095
• XenbaseID: XB-GENE-1013521
• Length: 981
• Species: Xenopus tropicalis
• Alignment Length: 978
• Identity: 760/978 - (77%)
• Similarity: 869/978 - (88%)
• Gaps: 1/978 - (0%)

Human     1 MASSHSSSPVPQGSSSDVFFKIEVDPSKHIRPVPSLPDVCPKEPTGDSHSLYVAPSLVTDQHRWT 65
            ||||||||.||..:|:..|:|..:.|::.:..|.|||||||||||||:.||...||:|.|||:||
 Frog     4 MASSHSSSLVPHSNSNKAFYKKGLQPAQQVGMVRSLPDVCPKEPTGDTKSLRDEPSVVADQHKWT 68

Human    66 VYHSKVNLPAALNDPRLAKRESDFFTKTWGLDFVDTEVIPSFYLPQISKEHFTVYQQEISQREKI 130
            :|:|||||||||||||||||||||||||||.|||::||:||.|||.|:||.|..|.|:...|||.
 Frog    69 IYNSKVNLPAALNDPRLAKRESDFFTKTWGQDFVESEVLPSPYLPAITKEQFLSYSQQTISREKN 133

Human   131 HERCKNICPPKDTFERTLLHTHDKSRTDLEQVPKIFMKPDFALDDSLTFNSVLPWSHFNTAGGKG 195
            ||:||::||.|..|:|.......|||.||||||||||||||||:||||||:|||||||::|||||
 Frog   134 HEKCKSVCPLKVDFDRPAYSHVLKSRADLEQVPKIFMKPDFALEDSLTFNAVLPWSHFSSAGGKG 198

Human   196 NRDAASSKLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLRKTSQAVKMLRDKIA 260
            :|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||:
 Frog   199 SRDAASSKLLQEKLSHYLDIVEVNIAHQISLRSEAFFHAMTSQHELQDYLRKTSQAVKMLRDKIS 263

Human   261 QIDKVMCEGSLHILRLALTRNNCVKVYNKLKLMATVHQTQPTVQVLLSTSEFVGALDLIATTQEV 325
            |||:|||||||.|||.|||||||:|:||||||||||||||||||:||||||:|||||||||||||
 Frog   264 QIDRVMCEGSLRILRQALTRNNCIKIYNKLKLMATVHQTQPTVQLLLSTSEYVGALDLIATTQEV 328

Human   326 LQQELQGIHSFRHLGSQLCELEKLIDKMMIAEFSTYSHSDLNRPLEDDCQVLEEERLISLVFGLL 390
            ||||||||||||||.|||||:|||||||:|:||::|:.||||||||:|..|:|||||:|||||:|
 Frog   329 LQQELQGIHSFRHLSSQLCEMEKLIDKMIISEFTSYARSDLNRPLEEDSHVVEEERLVSLVFGML 393

Human   391 KQRKLNFLEIYGEKMVITAKNIIKQCVINKVSQTEEIDTDVVVKLADQMRMLNFPQWFDLLKDIF 455
            |||||:|.|||.::|:.||||||||||:|.|||.||||::||.||.||:||:||.|||.||::||
 Frog   394 KQRKLDFFEIYSDEMMATAKNIIKQCVVNTVSQIEEIDSEVVTKLTDQIRMMNFSQWFGLLQNIF 458

Human   456 SKFTIFLQRVKATLNIIHSVVLSVLDKNQRTRELEEISQQKNAAKDNSLDTEVAYLIHEGMFISD 520
            ||||||::||||||::|.:|||.|||||||.||:|.::.|:|..:::::|.|:|||.|||:||||
 Frog   459 SKFTIFIERVKATLSVIRNVVLMVLDKNQRVREMEMLAAQQNLRRESNVDNELAYLTHEGLFISD 523

Human   521 AFGEGELTPIAVDTTSQRNASP-NSEPCSSDSVSEPECTTDSSSSKEHTSSSAIPGGVDIMVSED 584
            |||||||...|..|..|||.|| :|||..||:||:||||||||||||||..|...||::|:::|:
 Frog   524 AFGEGELPNAATSTNFQRNTSPSSSEPSGSDTVSDPECTTDSSSSKEHTLPSVTQGGIEIILTEE 588

Human   585 MKLTDSELGKLANNIQELLYSASDICHDRAVKFLMSRAKDGFLEKLNSMEFITLSRLMETFILDT 649
            |||||.||||:||:||||||.||||||||.||||::|||:||||||||.||::|||.:|.|:|.|
 Frog   589 MKLTDLELGKIANSIQELLYDASDICHDRCVKFLLARAKEGFLEKLNSAEFVSLSRAVEAFVLGT 653

Human   650 EQICGRKSTSLLGALQSQAIKFVNRFHEERKTKLSLLLDNERWKQADVPAEFQDLVDSLSDGKIA 714
            |:||||:|.||.|||||||.|||||||:||||||||||||||||||||||||||||||:.||||.
 Frog   654 EKICGRRSMSLRGALQSQANKFVNRFHDERKTKLSLLLDNERWKQADVPAEFQDLVDSIKDGKIV 718

Human   715 LPEKKSGATEERKPAEVLIVEGQQYAVVGTVLLLIRIILEYCQCVDNIPSVTTDMLTRLSDLLKY 779
            |||:|||.||||||.:.|.|:||:||||||||||||||||||.|||:||||||||||||||||||
 Frog   719 LPERKSGGTEERKPTDFLTVDGQKYAVVGTVLLLIRIILEYCSCVDDIPSVTTDMLTRLSDLLKY 783

Human   780 FNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPVIRAHFEARLPPKQYSMLRHFD 844
            |||||||||||||||||||||||||||||||||||||||||||:||||||||:.|||||||||||
 Frog   784 FNSRSCQLVLGAGALQVVGLKTITTKNLALSSRCLQLIVHYIPLIRAHFEARMQPKQYSMLRHFD 848

Human   845 HITKDYHDHIAEISAKLVAIMDSLFDKLLSKYEVKAPVPSACFRNICKQMTKMHEAIFDLLPEEQ 909
            ||||||:|||||||||||.|||.||:||||||||||||||.|||.|||||.||||||:|||||||
 Frog   849 HITKDYNDHIAEISAKLVTIMDGLFEKLLSKYEVKAPVPSTCFRTICKQMAKMHEAIYDLLPEEQ 913

Human   910 TQMLFLRINASYKLHLKKQLSHLNVINDGGPQNGLVTADVAFYTGNLQALKGLKDLDLNMAEIWE 974
            ||.|||:||:||..||::||.|||||||||||.|||.||:||||.|:|||||||||||::|||||
 Frog   914 TQTLFLKINSSYIFHLRRQLCHLNVINDGGPQYGLVAADIAFYTENVQALKGLKDLDLSLAEIWE 978

Human   975 QKR 977
            |||
 Frog   979 QKR 981

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VPS54	NP_057600.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	535..575		27/40 (68%)
		Vps54	737..865	CDD:462318	119/127 (94%)
vps54	XP_002939365.2	Vps54	741..869	CDD:462318	119/127 (94%)