Protein Alignment ZCCHC17 and mog-5

DIOPT Version :10

• Sequence 1: NP_001269495.1
• Gene: ZCCHC17 / 51538
• HGNCID: 30246
• Length: 263
• Species: Homo sapiens
• Sequence 2: NP_495019.1
• Gene: mog-5 / 173920
• WormBaseID: WBGene00003393
• Length: 1200
• Species: Caenorhabditis elegans
• Alignment Length: 283
• Identity: 65/283 - (22%)
• Similarity: 110/283 - (38%)
• Gaps: 78/283 - (27%)

Human    45 VAMVTDYGAFIKIPGCR--KQGLVHRTHMSSCRVDKPSEIVDVGDKVWVKLIGREMKNDRIKVSL 107
            |..:..:||||.:.|.|  ::||||.:.:.:.||...::::..|:.|.||:  .:::|.  |:||
 Worm   241 VNSIQSFGAFITLEGFRQKQEGLVHISQIRNERVQTVADVLKRGENVKVKV--NKIENG--KISL 301

Human   108 SMKVVNQGTGKDLDPNNVIIEQEE--RRRRSFQDYTGQKITLEA-----------------VLNT 153
            |||.|:|.:|:||:|....:..:.  .|.|:....|...:..||                 |..:
 Worm   302 SMKEVDQNSGEDLNPRETDLNPDAIGVRPRTPPASTSSWMNPEASGVGQGPSTSIGGGKARVRIS 366

Human   154 TCKKCGCKGHFAKDCFMQPGGTKYSL-IPDEEEE---------KEEAKSAEFE----KPD----- 199
            |.::...:.       ||..|...:. :||.:||         :.:.:..|.|    :||
 Worm   367 TPERWELRQ-------MQGAGVLTATDMPDFDEEMGVLRNYDDESDGEDIEIELVEDEPDFLRGY 424

Human   200 -----------PTRNPS-------------RKRKKEKKKKKHRDRKSSDSDSSDSESDTGKRARH 240
                       ..:||.             .|.:||.|.:..|:|   |.|:....|...:....
 Worm   425 GKGGAEIEPVKVVKNPDGSLAQAALMQGALSKERKETKIQAQRER---DMDTQKGFSSNARILDP 486

Human   241 TSKDSKAAKKKKKKKKHKKKHKE 263
            .|.:...|....:.|....|.||
 Worm   487 MSGNQSTAWSADESKDRNNKMKE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZCCHC17	NP_001269495.1	S1_pNO40	45..108	CDD:240191	20/64 (31%)
mog-5	NP_495019.1	GH2-like_DHX8	4..73	CDD:409668
		S1_DHX8_helicase	234..311	CDD:240189	26/73 (36%)
		HrpA	538..>1157	CDD:441249