Protein Alignment GPR89B and YHR078W

DIOPT Version :10

• Sequence 1: NP_057418.1
• Gene: GPR89B / 51463
• HGNCID: 13840
• Length: 455
• Species: Homo sapiens
• Sequence 2: NP_011945.1
• Gene: YHR078W / 856477
• SGDID: S000001120
• Length: 552
• Species: Saccharomyces cerevisiae
• Alignment Length: 540
• Identity: 108/540 - (20%)
• Similarity: 210/540 - (38%)
• Gaps: 164/540 - (30%)

Human    25 FMRQLFKDYEIRQYVV----QVIFSVTFAFSCTMFELIIFEI--LGVLNSSSRYFHWKMNLCVIL 83
            |:.:.:.:|.:..:.|    :|:||:.........|:|:::|  .|:....:....|...|..|:
Yeast    65 FINKFYTEYSLPSHKVLQSLRVLFSLAMMTYTVTIEIILWQIKVAGMDKEVTFITTWVWPLTAIM 129

Human    84 L--ILVFMVPFYIGYFIVSNIRLLHKQR------LLFSCLLWLTF--MYFFWKLGDPFPILSPKH 138
            |  ||:...||:|   |:|.:...:..:      ::.:|::..|.  :..:..:| ||..
Yeast   130 LSFILILFQPFFI---IISLLNKFYNDKFDIDRLIIVTCIILSTLIALLSYINIG-PFQY----- 185

Human   139 GILSIEQLISRVGVIGVTLMALLSGFGAV---------------NCPYTYMSYFLRNVTDTDILA 188
                .:.:::|:.:.|||:||.|||...|               |.|.:..|:  ||:.:::  .
Yeast   186 ----TKNILTRLSIGGVTVMASLSGLATVSSLYYNFLVIWHKFRNTPMSDPSF--RNINNSN--N 242

Human   189 LERRLLQTMDMIISKK---------KRMAMARRTMFQKGEVHNKPSGFWGMIKSVTTSASGSENL 244
            ..:.||.|.|..|.:|         :.:.:.|....:.||             :.|..|...|.:
Yeast   243 NSKSLLWTTDAYIEEKIQDYEHNIEQNVQILRSLEEEVGE-------------NSTFKAELMEKI 294

Human   245 TLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGYFFSIYCVWKIFMATINIV 309
            ...|.|:..||.|.:|              ....:||| |.|. :|  |.|||:.|:.:..:..:
Yeast   295 AWYQLELGKLEALLQQ--------------SPQVRTFK-KAFE-VG--FIIYCLHKLIITFLKRI 341

Human   310 ------------------FDRVGKTDPVTRGIEITV-NYLGIQFDVKFWSQH------------- 342
                              |.....:||    :.||: |.|...| .:|..||
Yeast   342 PYIIYHSLKYPDDYDYENFSENAASDP----LAITIANILDFSF-FRFNYQHDLDSLTKQISLFL 401

Human   343 -ISFILVGIIIVTSIRGLLITL--TKF----FYAISSSKSSNVIV-------------------- 380
             ||..|..:..|.:....::||  .||    .:|:.:..::||:.
Yeast   402 SISLFLCCLSAVNTTISYVVTLLPIKFQILALFAMQNDDTANVLPEYTNNSSYKGKKRNYSQEQK 466

Human   381 -------LLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLGELQFN----FYHRWFDVIFLVSA 434
                   |:::::.|:|.:::.|::|..:|.|....:.|:||. :|.    ....|||.::..:.
Yeast   467 GISLIKNLVVSELTGVYVLATTLMVRSHLPFEVSQRLKELLGG-KFTVPNIVIDSWFDEVYAFAC 530

Human   435 LSSILFLYLAHKQAPEKQMA 454
            :.:.:.:.:|.::...|:::
Yeast   531 VFTFICIRIAERKLSTKKVS 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GPR89B	NP_057418.1	GPHR_N	140..207	CDD:463623	21/90 (23%)
		ABA_GPCR	276..446	CDD:463577	48/239 (20%)
YHR078W	NP_011945.1	GPHR_N	183..262	CDD:463623	22/91 (24%)
		ABA_GPCR	309..542	CDD:463577	49/256 (19%)