Protein Alignment SFMBT1 and Sfmbt1

DIOPT Version :10

• Sequence 1: NP_057413.2
• Gene: SFMBT1 / 51460
• HGNCID: 20255
• Length: 866
• Species: Homo sapiens
• Sequence 2: NP_113835.2
• Gene: Sfmbt1 / 58967
• RGDID: 61999
• Length: 863
• Species: Rattus norvegicus
• Alignment Length: 866
• Identity: 767/866 - (88%)
• Similarity: 811/866 - (93%)
• Gaps: 3/866 - (0%)

Human     1 MNGEQQLDADAGSGMEEVELSWEDYLEETGSTAVPYGSFKHVDTRLQNGFAPGMKLEVAVRTDPE 65
            ||||||||||.|||:|..|.||||||||||:|..||.||||||..||:|||||||||||:|.|||
  Rat     1 MNGEQQLDADLGSGVEVEEFSWEDYLEETGATTAPYASFKHVDICLQSGFAPGMKLEVALRKDPE 65

Human    66 TYWVATVITTCEQLLLLRYDGYGEDRRADFWCDIRKADLYPIGWCEQNKKTLEAPEGIRDKVSDW 130
            |||||||||.|||||||||:||||||:||||||||:|.|||||||:|||||||||||||||||||
  Rat    66 TYWVATVITACEQLLLLRYEGYGEDRKADFWCDIRRAGLYPIGWCQQNKKTLEAPEGIRDKVSDW 130

Human   131 DEFLRQTLIGACSPPVPLLEGLRNGRNPLDLIAPGSRLECQAFQDSLSTWIVTVVENIGGRLKLR 195
            ..||::||.|||.|||.||||||||||||||||||||||||.|:||:|||||||||||||||||:
  Rat   131 SAFLQRTLTGACGPPVALLEGLRNGRNPLDLIAPGSRLECQDFRDSVSTWIVTVVENIGGRLKLQ 195

Human   196 YEGLESSDNYEHWLYYLDPFLHHVGWAAQQGYELQPPSAIRHLKNEAEWQEILAKVKEEEEEPLP 260
            |||||..|.:|||||||||||||:|||||||||||||.|||||||||:||||||:||  ||||||
  Rat   196 YEGLERHDGFEHWLYYLDPFLHHIGWAAQQGYELQPPLAIRHLKNEADWQEILARVK--EEEPLP 258

Human   261 SYLFKDKQVIGIHTFSVNMKLEAVDPWSPFGISPATVVKVFDEKYFLVEMDDLRPENHARRSFVC 325
            ||||||||||..|.||:|||||||||||||||||||:.||||:||||||:||||||:||||||||
  Rat   259 SYLFKDKQVIRTHEFSINMKLEAVDPWSPFGISPATIAKVFDDKYFLVEIDDLRPEDHARRSFVC 323

Human   326 HADSPGIFPVQWSLKNGLHISPPPGYPSQDFDWADYLKQCGAEAAPQRCFPPLISEHEFKENMKL 390
            ||:|||||||||||||||||:||||:.||||||||||||||||||||:|||..:|||:|||||||
  Rat   324 HANSPGIFPVQWSLKNGLHINPPPGFRSQDFDWADYLKQCGAEAAPQKCFPQSVSEHQFKENMKL 388

Human   391 EAVNPILPEEVCVATITAVRGSYLWLQLEGSKKPIPECIVSVESMDIFPLGWCETNGHPLSTPRR 455
            |||||:.||||.:||:||||||||||||||||||:||.|||||||:|||||||||||||||||||
  Rat   389 EAVNPLFPEEVSIATVTAVRGSYLWLQLEGSKKPVPEFIVSVESMNIFPLGWCETNGHPLSTPRR 453

Human   456 ARVYKQRKIAVVQPEKQVPSSRTVHEGLRNQELNSTESVMINGKYCCPKIYFNHRCFSGPYLNKG 520
            ||.:|.|||||||||||:.|||||||||:|| |||..||||||||||||||||||||||||||||
  Rat   454 ARGHKLRKIAVVQPEKQILSSRTVHEGLKNQ-LNSPHSVMINGKYCCPKIYFNHRCFSGPYLNKG 517

Human   521 RIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRA 585
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   518 RIAELPQCVGPGNCVLVLREVLTLLINAAYKPSRVLRELQLDKDSVWHGCGEVLKAKYKGKSYRA 582

Human   586 TVEIVKTADRVTEFCRQTCIKLECCPNLFGPRMVLDKCSENCSVLTKTKYTHYYGKKKNKRIGRP 650
            |||||:||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||
  Rat   583 TVEIVRTADRVTEFCRQTCIKLECCPNLFGPRMVLDTCSENCSVLTKTKYTHYYGKKKNKRIGRP 647

Human   651 PGGHSNLACALKKASKRRKRRKNVFVHKKKRSSASVDNTPAGSPQGSGGEDEDDPDEGDDDSLSE 715
            |||||||:|||||.|||||||||:||||||||||||||||.|||||||||||||.|:||||||:|
  Rat   648 PGGHSNLSCALKKTSKRRKRRKNIFVHKKKRSSASVDNTPVGSPQGSGGEDEDDADDGDDDSLTE 712

Human   716 GSTSEQQDELQEESEMSEKKSCSSSPTQSEISTSLPPDRQRRKRELRTFSFSDDENKPPSPKEIR 780
            ||||||||||.||||:|||||||.||||||:||.||||.|..|||.:|.|.||.|||||||||||
  Rat   713 GSTSEQQDELHEESEVSEKKSCSPSPTQSEMSTPLPPDTQTDKREAQTSSLSDGENKPPSPKEIR 777

Human   781 IEVAERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGP 845
            |||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   778 IEVDERLHLDSNPLKWSVADVVRFIRSTDCAPLARIFLDQEIDGQALLLLTLPTVQECMDLKLGP 842

Human   846 AIKLCHHIERIKFAFYEQFAN 866
            |||||||||||||||||||||
  Rat   843 AIKLCHHIERIKFAFYEQFAN 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SFMBT1	NP_057413.2	MBT 1	20..120		83/99 (84%)
		Antigenic epitope	34..42		5/7 (71%)
		MBT_SFMBT1_rpt1	47..140	CDD:439101	79/92 (86%)
		MBT 2	128..232		87/103 (84%)
		MBT_SFMBT1_rpt2	159..257	CDD:439103	83/97 (86%)
		MBT 3	242..348		90/105 (86%)
		MBT_SFMBT1_rpt3	273..366	CDD:439105	81/92 (88%)
		MBT 4	356..453		83/96 (86%)
		MBT_SFMBT1_rpt4	382..471	CDD:439107	76/88 (86%)
		SLED	502..617	CDD:463469	113/114 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	641..777		115/135 (85%)
		SAM_Scm-like-4MBT1,2	782..866	CDD:188980	82/83 (99%)
Sfmbt1	NP_113835.2	MBT 1	20..120		83/99 (84%)
		MBT	47..140	CDD:459242	79/92 (86%)
		MBT 2	128..232		87/103 (84%)
		MBT_SFMBT1_rpt2	159..255	CDD:439103	83/97 (86%)
		MBT 3	242..346		90/105 (86%)
		MBT_SFMBT1_rpt3	271..364	CDD:439105	81/92 (88%)
		MBT 4	354..451		83/96 (86%)
		MBT	380..469	CDD:459242	76/88 (86%)
		SLED	499..614	CDD:463469	113/114 (99%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	638..773		114/134 (85%)
		SAM_Scm-like-4MBT1,2	779..863	CDD:188980	82/83 (99%)