DRSC/TRiP Functional Genomics Resources

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Protein Alignment IP6K2 and Ip6k

DIOPT Version :10

Sequence 1:XP_006713262.1 Gene:IP6K2 / 51447 HGNCID:17313 Length:485 Species:Homo sapiens
Sequence 2:NP_726095.2 Gene:Ip6k / 37465 FlyBaseID:FBgn0034644 Length:902 Species:Drosophila melanogaster


Alignment Length:452 Identity:143/452 - (31%)
Similarity:201/452 - (44%) Gaps:137/452 - (30%)


- Green bases have known domain annotations that are detailed below.


Human    33 TDKQQTEDVLAAGLRCLPHLPAICARRMSPAFR----AMDVEPRAKGVLLEPFVHQVGGHSCVLR 93
            |..|:.:.:|      ||...|..|..:..:.:    :.|:......|.|.|..:|||||:.:|.
  Fly   140 TKPQKQKPLL------LPEAAASTATAVGKSSKNPQLSKDLLDNEDEVALHPLSNQVGGHTRLLL 198

Human    94 FNETTLCKPLVPREHQFYETLPAEMRKFTPQYKGVV--------------SVRFEEDEDRNLCLI 144
            .|::|:.|||..||..||:.:|.::.||.|:||||:              |..|.:|      ..
  Fly   199 LNQSTVIKPLNLRELDFYQNIPQDILKFVPKYKGVMQATTMGGAKLDKRYSPSFRDD------AA 257

Human   145 AYPLKGDHGIVDIVDNSDCEPKSKLLRWTTNKKHHVLETEKTPKDWVRQHRKEEKMKSHKLEEEF 209
            |.|::                                                 ||.:.|     
  Fly   258 AVPVR-------------------------------------------------KMSASK----- 268

Human   210 EWLKKSEVLYYTVEKKGNISSQLKHYNPWSMKCHQQQLQRMKENAKHRNQYKFILLENLTSRYEV 274
              .|:.|||...|.|.|..:..:|..:         ||.       :.|:..|::|||:||::..
  Fly   269 --RKRDEVLRMKVHKNGQAAEVIKSIS---------QLD-------NTNKQYFLMLENITSQFRN 315

Human   275 PCVLDLKMGTRQHGDDASEEKAANQIRKCQQSTSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRKL 339
            ||:|||||||||||||||.||.:.|:.||..|||..:|||:||||.|.|...|....:||.||:|
  Fly   316 PCILDLKMGTRQHGDDASAEKRSKQMAKCAASTSGSLGVRLCGMQTYLADLEQYAKRDKYWGREL 380

Human   340 SVQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQESYRFYSSSLLVIYDGKER----- 399
            :..|||.||..|||||..||..::..:|::|.:|:.|:|:|.||||||.|||::|:|.|.     
  Fly   381 NEGGFKTALHDFFHNGYRLRIRVIRKILQRLLQLRRVIEKQSSYRFYSCSLLIVYEGFEENPMAP 445

Human   400 ------------------PEVVLD------SDAEDLEDLSEESADESAGAYAYKPIGASSVD 437
                              |..|.|      .|.:||||      |:.||..|...:.|...|
  Fly   446 PPSMSQDEWPEAPRSATVPGTVFDYHPENSIDEDDLED------DDEAGNEAGDELEAHDTD 501

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IP6K2XP_006713262.1 IPK 262..477 CDD:397715 90/205 (44%)
Ip6kNP_726095.2 IPK 303..>437 CDD:397715 74/133 (56%)
IPK <846..894 CDD:416457
Blue background indicates that the domain is not in the aligned region.

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