DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment IP6K2 and IP3K1

DIOPT Version :10

Sequence 1:XP_006713262.1 Gene:IP6K2 / 51447 HGNCID:17313 Length:485 Species:Homo sapiens
Sequence 2:NP_609313.2 Gene:IP3K1 / 34300 FlyBaseID:FBgn0032147 Length:441 Species:Drosophila melanogaster


Alignment Length:414 Identity:84/414 - (20%)
Similarity:142/414 - (34%) Gaps:162/414 - (39%)


- Green bases have known domain annotations that are detailed below.


Human   158 VDNSDCEPKSKLLRWTTNKKHHV--------------------LETEKTPKDWVRQHRKEEKMKS 202
            :.|.:|:..| |.|.....|:|:                    |....||.  :.||:     ::
  Fly    95 IPNENCDYLS-LQRSGQAPKNHIQAQDPAQMSLLKFLAINALELSAPATPH--LLQHQ-----QA 151

Human   203 HKLEEEFEWLKKS---EVLYYT----VEKK--GNISSQLKHYNPWSMKCHQQQ----------LQ 248
            ||..:...|::.|   |.:..|    |.|:  |...|::..|.   :.|.:.|          :|
  Fly   152 HKQAKPQGWMQLSGHPESIVPTSTGIVRKRISGLEDSEVHAYR---LICKEPQTAQIVPAYFGIQ 213

Human   249 RMKENAKHRNQYKFILLENLTSRYEVPCVLDLKMGTR-----------------------QHGDD 290
            .|:  ::|     ||.|::|.:.:..|||:|:|||:|                       ..|..
  Fly   214 EMQ--SQH-----FIELQDLLAGFRDPCVMDIKMGSRTFLESEVSNATLRPDLYQKMIAVDAGAP 271

Human   291 ASEEKAANQIRKCQQ-------STSAVIGVRVCGMQVYQAGSGQLMFMNKYHGRK--------LS 340
            ...|..|..|.|.:.       |:|...|.|:..:::              .||.        .|
  Fly   272 TPAEHEARAITKLRYMTFRESLSSSHSKGFRIEALRL--------------RGRPPVKDLKTCRS 322

Human   341 VQGFKEALFQFFHNGRYLRRELLGPVLKKLTELKAVLERQ---ESYRFYSSSLLVIYDGKERPEV 402
            .:...:.:.||....|.:::||    ||:|..::.|:|:.   .|:....||:.::||       
  Fly   323 SEQIAQTIEQFLAARRSVQKEL----LKRLKHMRLVIEQSTFFASHEIIGSSIFIVYD------- 376

Human   403 VLDSDAEDLEDLSEESADESAGAYAYKPIGASSVDVRMIDFAHTTCR-LYGEDTVVHE------G 460
                             |:..|.:             :||||  .|| |.....|.|.      .
  Fly   377 -----------------DDRVGVW-------------LIDFA--KCRELPPHVRVDHRSAWAPGN 409

Human   461 QDAGYIFGLQSLIDIVTEISEESG 484
            ::.|.:.|:..||....|:....|
  Fly   410 REEGLLRGMDELIRSFEEVYARCG 433

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IP6K2XP_006713262.1 IPK 262..477 CDD:397715 54/262 (21%)
IP3K1NP_609313.2 IPK 220..426 CDD:397715 54/262 (21%)

Return to query results.
Submit another query.