| Sequence 1: | NP_057342.2 | Gene: | YTHDF2 / 51441 | HGNCID: | 31675 | Length: | 579 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_647811.2 | Gene: | Ythdc1 / 38420 | FlyBaseID: | FBgn0027616 | Length: | 721 | Species: | Drosophila melanogaster |
| Alignment Length: | 377 | Identity: | 87/377 - (23%) |
|---|---|---|---|
| Similarity: | 153/377 - (40%) | Gaps: | 63/377 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Human 215 SITSNIVASNSLPPATIAPPKPASWADIASKPAKQ--QPKLKTKNGIAG----SSLPPPP----- 268
Human 269 --IKHNMDIGTWDNKGPVAKAPSQALVQNIGQPTQGSPQPVGQQANNS-PPVAQASVGQQTQPLP 330
Human 331 PPPPQPAQLSVQQQAAQPTRWVAPRNRGSGFGHNGVDGNGVGQSQAGSGSTPSEPHPVLEKLRSI 395
Human 396 NNYNPKDFDWNLK------HGRVFIIKSYSEDDIHRSIKYNIWCSTEHGNKRLDAAYRSMNGKGP 454
Human 455 VYLLFSVNGSGHFCGVAEMKSAVDYNTCAGVW------SQDKWKGRFDVRWIFVKDVPNSQLRHI 513
Human 514 RLENNENKPVTNSRDTQEV------------PLEKAKQVLKIIASYKHTTSI 553 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| YTHDF2 | NP_057342.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..45 | ||
| Localization to mRNA processing bodies (P-bodies). /evidence=ECO:0000269|PubMed:24284625 | 2..384 | 40/182 (22%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 247..387 | 32/153 (21%) | |||
| Interaction with m6A-containing mRNAs. /evidence=ECO:0000269|PubMed:24284625 | 385..579 | 46/193 (24%) | |||
| YTH | 411..544 | CDD:461195 | 39/150 (26%) | ||
| Ythdc1 | NP_647811.2 | YTH | 255..391 | CDD:410979 | 38/138 (28%) |
| Blue background indicates that the domain is not in the aligned region. | |||||