Protein Alignment HPCAL4 and CG2256

DIOPT Version :10

• Sequence 1: NP_057341.1
• Gene: HPCAL4 / 51440
• HGNCID: 18212
• Length: 191
• Species: Homo sapiens
• Sequence 2: NP_572437.2
• Gene: CG2256 / 31727
• FlyBaseID: FBgn0029995
• Length: 324
• Species: Drosophila melanogaster
• Alignment Length: 210
• Identity: 47/210 - (22%)
• Similarity: 93/210 - (44%)
• Gaps: 36/210 - (17%)

Human     1 MGKTNSKLAPEVLEDLVQNTEFSEQELK---QWYKGFLKDCPSGILNLEE--------------- 47
            |.:.:.|:.|::|:.|.:.|.|::.||.   :.|:..:.:|......|..
  Fly   101 MDELSGKVNPKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVE 165

Human    48 ------FQQLYIKFFPYGDASKFAQHAFRTFDKNGDG-TIDFREFICALSVTSRGSFEQKLNWAF 105
                  |::|....|.........:..|.::||..:| .:....::..||...||:..::..:.|
  Fly   166 GIDRIVFRELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPAERAAFCF 230

Human   106 EMYDLDGDGRITRLEMLEIIEAIYKMVGTVIMMRMNQD---GLTPQQRVDKIFKKMDQDKDDQIT 167
            .:|||:.||.||:.||..::.      ..:|....::|   |:  :..|:.:.||.|.|||.:::
  Fly   231 RVYDLNTDGFITKDEMFTLLR------NCLIKQPQDEDPDEGV--KDLVEIVLKKFDLDKDGKVS 287

Human   168 LEEFKEAAKSDPSIV 182
            ||:|.....::|.::
  Fly   288 LEDFMGTVTAEPLLI 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HPCAL4	NP_057341.1	FRQ1	21..177	CDD:444056	40/183 (22%)
CG2256	NP_572437.2	PRK12309	<103..290	CDD:183426	43/194 (22%)
		EF-hand_7	224..292	CDD:463900	22/75 (29%)