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Protein Alignment SNX9 and lst-4

DIOPT Version :10

Sequence 1:	NP_057308.1	Gene:	SNX9 / 51429	HGNCID:	14973	Length:	595	Species:	Homo sapiens
Sequence 2:	NP_001379029.1	Gene:	lst-4 / 178361	WormBaseID:	WBGene00003086	Length:	592	Species:	Caenorhabditis elegans

Alignment Length:	564	Identity:	171/564 - (30%)
Similarity:	275/564 - (48%)	Gaps:	64/564 - (11%)

- Green bases have known domain annotations that are detailed below.

Human    59 ILPSDGKDQFSCG-NSVADQAFLDS--LSASTAQASSSAASNNHQVGSGNDPWSAWSASKSGNWE 120
            ||..:..:|.|.| :|....:|..|  :|.|.........|:.....|.. |:..|..:..
Worm    62 ILMEEEDEQHSTGKHSSRKSSFKKSGAISKSVLPPPLPPTSSGPPAASSR-PFDDWGGASE---- 121

Human   121 SSEGWGAQPEGAGAQRNTN-TPNNWDTAFGHPQAYQGPATGDDDDWDEDWD-------------- 170
                 .|.|...|||.:.. ||:       .|:..:......:||:|::|.
Worm   122 -----VAAPPSYGAQHHHQPTPS-------VPEVTRSSYPSQNDDFDDEWTDEDDEQEPTRPNVQ 174

Human   171 ---GPKSSSYFKDSESADAGGAQRGNSRASSSSMKIPLNKFPGFAKPGTEQYLL--AKQLAKPKE 230
               |..|......|.| :.||..||:::.:.:     :|:|..|.|.|.|.|::  :|..::..|
Worm   175 SSIGSNSRRDLSRSHS-EHGGPDRGSNKVNKN-----INRFSNFVKSGVEAYVIGESKTTSQISE 233

Human   231 KIPIIVGDYGPMWVYPTSTFDCVVADPRKGSKMYGLKSYIEYQLTP--TNTNRSVNHRYKHFDWL 293
            :..:::.:....|......:.|:|..|:|.||:.||||:|.|.:|.  ||..|.|:.||||||||
Worm   234 RHEVVMNNGIIQWKPIQQYYTCIVDKPKKESKLKGLKSFIAYSITSSLTNIQRQVSRRYKHFDWL 298

Human   294 YERLLVKFGSAIPIPSLPDKQVTGRFEEEFIKMRMERLQAWMTRMCRHPVISESEVFQQFLNFRD 358
            :|:|..|: ..||||.||:|||.||:||:.|..|...||.|:.::|||||:|:|||:..|::..|
Worm   299 HEQLSAKY-VLIPIPPLPEKQVAGRYEEDLIDHRKHILQLWVNKICRHPVLSQSEVWLHFISCTD 362

Human   359 EKEWKTGKRKAERDE-LAGVMIFSTMEPEAPDLDLVEIEQKCEAVGKFTKAMDDGVKELLTVGQE 422
            ||:||.|||:||:|| :.|..:.....|..| ||...::.:.|...:..|..:    |.:.|.||
Worm   363 EKDWKNGKRRAEKDEYIGGAFLNCITVPHQP-LDPNNVDMQVERFQRSVKTSE----EAMRVMQE 422

Human   423 HW----KRCTGPLPKEYQKIGKALQSLATVFSSSGYQGETDLNDAITEAGKTYEEIASLVAEQPK 483
            ..    |...||:.:.:||:|.|.::|...|..........|.:|:......|.||..:.....|
Worm   423 RMNMFQKVFAGPVKQNWQKMGSAFKTLQQSFEIDETVASRRLTEALAYTASEYHEIGQVFDAHTK 487

Human   484 KDLHFLMECNHEYKGFLGCFPDIIGTHKGAIEKVKESDKLVATSKITLQDKQNMVKRVSIMSYAL 548
            .|:..::|..:.|||.:...||||..||.|::|.::|:     .:::..:.:.|.:|:..|||.:
Worm   488 NDMEPVLENLYSYKGTVQNVPDIIQVHKQAVQKFRDSE-----GRLSSAEAEKMKQRIDAMSYTV 547

Human   549 QAEMNHFHSNRIYDYNSVIRLYLEQQVQFYETIAEKLRQALSRF 592
            .||:.|..:.::.|..|.:..||::|..||:.:|.||....:|:
Worm   548 IAEVQHQTAEKVEDMKSTMGTYLKKQAMFYQEVATKLTSLAARY 591

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.