Protein Alignment HEMK1 and HemK2

DIOPT Version :10

• Sequence 1: XP_011532108.1
• Gene: HEMK1 / 51409
• HGNCID: 24923
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_001027221.1
• Gene: HemK2 / 3771966
• FlyBaseID: FBgn0031454
• Length: 224
• Species: Drosophila melanogaster
• Alignment Length: 158
• Identity: 42/158 - (26%)
• Similarity: 68/158 - (43%)
• Gaps: 20/158 - (12%)

Human   162 LILEVGCGSGAISLSLLSQLPQ-SRVIAVDKREAAISLTHENAQR--LRLQDRIWIIHLDMTSER 223
            |.:|:|.|||.|..:|..:|.. |..:|.|....|.:.|...|.|  .|| |.|.....|....|
  Fly    45 LCVELGSGSGVIITALAKKLAGFSLCLATDINPKACNATRRTATRNGARL-DSIRCSLADALRPR 108

Human   224 SWTHLPWGPMDLIVSNPPYVFHQDMEQLAPEIRSYEDPA-------ALDGGEEGMDIITHILALA 281
            |        :|:::.|||||...|.|....:..|:.:.:       :..||::|..:...:|...
  Fly   109 S--------VDVLLFNPPYVVTSDEELQTQQFDSHSESSTDRNLVFSWAGGQDGRRVTDILLKQL 165

Human   282 PRLLKDSGSIF-LEVDPRHPELVSSWLQ 308
            ..:|...|.:: |.:....||.:..:|:
  Fly   166 DDILSPRGVLYLLLLRENKPEEIIKYLE 193

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HEMK1	XP_011532108.1	HemK	43..326	CDD:442135	42/158 (27%)
HemK2	NP_001027221.1	AdoMet_MTases	15..219	CDD:473071	42/158 (27%)