Protein Alignment HEMK1 and HemK1

DIOPT Version :10

• Sequence 1: XP_011532108.1
• Gene: HEMK1 / 51409
• HGNCID: 24923
• Length: 355
• Species: Homo sapiens
• Sequence 2: NP_609031.2
• Gene: HemK1 / 33902
• FlyBaseID: FBgn0031817
• Length: 323
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 101/286 - (35%)
• Similarity: 158/286 - (55%)
• Gaps: 16/286 - (5%)

Human    38 LSSAIELVSHWTGVFEKRGIPEARESSEYIVAHVLGAKTFQSLRPALWTQPLTSQQLQCIRELSS 102
            ::.|:| :..|....:..|:.:.:.:.:.||:|||..| |.|:..:.....|...||........
  Fly    33 VTKALE-IGQWEEKLKAAGVEDRKFNVKCIVSHVLKQK-FSSVPDSFDQLQLNPGQLADFERFLE 95

Human   103 RRLQRMPVQYILGEWDFQGLSLRMVPPVFIPRPETEELVEWVLEEVAQRSHAVGSPGSPLILEVG 167
            .|..|||:|:|:|||||..::|:..|.||||||||||.:..|:::.....|..       :||||
  Fly    96 ARCARMPLQHIIGEWDFMDITLKTSPSVFIPRPETEEFMRLVIDDHKNAKHVD-------LLEVG 153

Human   168 CGSGAISLSLLSQLPQSRVIAVDKREAAISLTHENAQRLRLQDRIWIIHLDMTSERSWTHLPWG- 231
            |||||:|||:|..|||....|:::.:||..|..|||:.|.|.:|..:.:..|..::   :||..
  Fly   154 CGSGAMSLSMLHSLPQVVATAIERSKAATVLAAENAKMLGLLNRFEVHNHTMEEDK---YLPEAL 215

Human   232 ---PMDLIVSNPPYVFHQDMEQLAPEIRSYEDPAALDGGEEGMDIITHILALAPRLLKDSGSIFL 293
               ..|||:||||||..::.:.|.||:..||:..|||||.:|:.:...:..||.|.|:..|.::|
  Fly   216 KDKKYDLIISNPPYVKTEEFQFLHPEVVVYENLNALDGGSDGLRVARLVFDLACRHLRPGGKLWL 280

Human   294 EVDPRHPELVSSWLQSRPDLYLNLVA 319
            |:...||.:|.:.:..:.:..|..:|
  Fly   281 ELGNDHPPMVKTIMNLKYEGRLKFIA 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HEMK1	XP_011532108.1	HemK	43..326	CDD:442135	100/281 (36%)
HemK1	NP_609031.2	HemK	46..322	CDD:442135	98/272 (36%)