Protein Alignment CSAD and Sply

DIOPT Version :10

• Sequence 1: XP_054228176.1
• Gene: CSAD / 51380
• HGNCID: 18966
• Length: 652
• Species: Homo sapiens
• Sequence 2: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 449
• Identity: 86/449 - (19%)
• Similarity: 149/449 - (33%)
• Gaps: 173/449 - (38%)

Human   156 LRSQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAG------RIITESLNTSQYT- 213
            |..:|.|:::||.    ::...:||||..:.:...||    |:.|      .::||....:.||
  Fly   103 LPEKGLSKEEILR----LVDEHLKTGHYNWRDGRVSG----AVYGYKPDLVELVTEVYGKASYTN 159

Human   214 ---YEIAPVFVLMEEEVLRKLRALV-GWSSGDGIFCPGGSISNMYAVNLAR-YQRYPDCKQRGLR 273
               .::.|....||.||:|....|. |.|:..|....||:.|.:.|:...| :.|    :.:|:.
  Fly   160 PLHADLFPGVCKMEAEVVRMACNLFHGNSASCGTMTTGGTESIVMAMKAYRDFAR----EYKGIT 220

Human   274 TLPPLALFTSKEVGKRHRPNPGLLILISSQLSRDLPGLLPALPTSSKASLPPGG-CASFQSRSVT 337
                             |||    |::               |.:..|:...|| ..:...|||
  Fly   221 -----------------RPN----IVV---------------PKTVHAAFDKGGQYFNIHVRSV- 248

Human   338 TPSRRELRFWDLAPTVSEWSRLMREGKWSPRIWRGRLVWPRLRLTFHFFETFILDSGAVPFLVSA 402
                      |:.|                                   ||:.:|   :.....|
  Fly   249 ----------DVDP-----------------------------------ETYEVD---IKKFKRA 265

Human   403 TSGTTVL----------GAFDPLEAIADVCQRHGLWLHVDAAWGGSVL-LSQTHRHLLD----GI 452
            .:..|:|          |..|.:||||.:..::.:.:||||..|..|: |.:...:.|.    .:
  Fly   266 INRNTILLVGSAPNFPYGTIDDIEAIAALGVKYDIPVHVDACLGSFVVALVRNAGYKLRPFDFEV 330

Human   453 QRADSVAWNPHKLLAAGLQCSALLLQD----------------------------TSNLLKRCHG 489
            :...|::.:.||...|....|.:|..|                            ...::..|..
  Fly   331 KGVTSISADTHKYGFAPKGSSVILYSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAACWA 395

Human   490 SQASYLFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLAR 548
            :..|:      .||..|:...::|...|.:             ::|: |.||..|:..:
  Fly   396 TMMSF------GYDGYLEATKRIVDTARYI-------------ERGV-RDIDGIFIFGK 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSAD	XP_054228176.1	DOPA_deC_like	185..648	CDD:99743	77/420 (18%)
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	77/416 (19%)