Protein Alignment CSAD and CG5618

DIOPT Version :9

• Sequence 1: XP_024304779.1
• Gene: CSAD / 51380
• HGNCID: 18966
• Length: 620
• Species: Homo sapiens
• Sequence 2: NP_649211.1
• Gene: CG5618 / 40241
• FlyBaseID: FBgn0036975
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 232/560 - (41%)
• Similarity: 322/560 - (57%)
• Gaps: 98/560 - (17%)

Human    93 REILMADSEALPSLAGDPVAVEALLRAVFGVVVDEAIQKGTSVSQKVCEWKEPEELKQLLDLELR 157
            |:.||.|.:.|.:       |..|||......||.  ||..  .||:..:.:|::||:|::|::|
  Fly    15 RDGLMDDWKILEN-------VFHLLRKEDTFCVDP--QKWD--KQKIVPFLQPDKLKELINLKVR 68

Human   158 -SQGESQKQILERCRAVIRYSVKTGHPRFFNQLFSGLDPHALAGRIITESLNTSQYTYEIAPVFV 221
             ::..|..:|.|.|:.||.|||||.|.||.||||..|||..|||.::||::|.|.||||:||||.
  Fly    69 ETENCSLAEIEELCQQVIHYSVKTSHGRFHNQLFGQLDPFGLAGALVTEAMNGSTYTYEVAPVFS 133

Human   222 LMEEEVLRKLRALVGWSSGDGIFCPGGSISNMYAVNLARYQRYPDCKQRGLRTLPPLALFTSKEV 286
            |:|.||:..:..|.|:..|||||.||||.||||.:.||||:..|:.|..|:..:.||.||||.|
  Fly   134 LIETEVIATICKLAGYKEGDGIFAPGGSTSNMYGMVLARYKIAPEVKTSGMFGMRPLVLFTSDE- 197

Human   287 GKRHRPNPGLLILISSH-------------------VTTPSRRELRFWDLAPTVSEWSRLMREGK 332
                           ||                   |.|..|.::...||...::|
  Fly   198 ---------------SHYSFVKAANWLGLGSYNCVSVRTNERGQMLLDDLEAKIAE--------- 238

Human   333 WSPRIWRGRLVWPRLRLTFHFFETFILDSGAVPFLVSATSGTTVLGAFDPLEAIADVCQRHGLWL 397
                        .:.|             |..||.|:.|:|||||||||.:...|||.:||||||
  Fly   239 ------------AKAR-------------GGEPFFVNCTAGTTVLGAFDDINGAADVTERHGLWL 278

Human   398 HVDAAWGGSVLLSQTHRHLLDGIQRADSVAWNPHKLLAAGLQCSALLLQDTSNLLKRCHGSQASY 462
            ||||..||:.|||..:|.|:.|::||:|.:|||||.:.|.||||..|.:::..||:||:.::|.|
  Fly   279 HVDACLGGAALLSAKNRSLIAGLERANSFSWNPHKTIGAPLQCSLFLTRESGRLLERCNSTEAHY 343

Human   463 LFQQDKFYDVALDTGDKVVQCGRRVDCLKLWLMWKAQGDQGLERRIDQAFVLARYLVEEMKKR-E 526
            ||||||||||:.|||:|.|||||::|..|.|||.||:|.......:|.|..:||.|..::::| :
  Fly   344 LFQQDKFYDVSYDTGNKSVQCGRKIDAFKFWLMLKARGYGKYGLMVDHAIHIARLLEGKLRQRGD 408

Human   527 GFELVM-EPEFVNVCFWFVPPSLR--GKQESPDYHERLSKVAPVLKERMVKEGSMMIGYQPHGTR 588
            .|.||: |.|:.||||||:|.::|  .::|:|::..||..|||.:||:|...|::||||.|...:
  Fly   409 RFRLVIPEHEYSNVCFWFIPKAMRVSSEEETPEWWSRLYTVAPKIKEQMAHSGTLMIGYSPLKAK 473

Human   589 --GNFFRVVVANSALTC------ADMDFLLNELERLGQDL 620
              |||||:|     .||      .::||:|:|:||||:.:
  Fly   474 NLGNFFRMV-----FTCFPILKSKELDFILDEIERLGEKI 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSAD	XP_024304779.1	DOPA_deC_like	185..616	CDD:99743	195/461 (42%)
CG5618	NP_649211.1	AAT_I	97..504	CDD:302748	195/461 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62386
OrthoDB	1	1.010	-	-		D162307at33208
OrthoFinder	1	1.000	-	-		FOG0000667
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100596
Panther	1	1.100	-	-	LDO	PTHR45677
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.830