Protein Alignment FZR1 and Fzr1

DIOPT Version :10

• Sequence 1: XP_016882352.1
• Gene: FZR1 / 51343
• HGNCID: 24824
• Length: 528
• Species: Homo sapiens
• Sequence 2: NP_001101544.2
• Gene: Fzr1 / 314642
• RGDID: 1308713
• Length: 493
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 483/496 - (97%)
• Similarity: 490/496 - (98%)
• Gaps: 3/496 - (0%)

Human    33 MDQDYERRLLRQIVIQNENTMPRVTEMRRTLTPASSPVSSPSKHGDRFIPSRAGANWSVNFHRIN 97
            |||||||||||||:||||||:|.|:|||||||||:||||||||||||||||||||||||||||||
  Rat     1 MDQDYERRLLRQIIIQNENTVPCVSEMRRTLTPANSPVSSPSKHGDRFIPSRAGANWSVNFHRIN 65

Human    98 ENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEKKGLFTY 162
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||
  Rat    66 ENEKSPSQNRKAKDATSDNGKDGLAYSALLKNELLGAGIEKVQDPQTEDRRLQPSTPEHKGLFTY 130

Human   163 SLSTKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDW 227
            |||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 SLSSKRSSPDDGNDVSPYSLSPVSNKSQKLLRSPRKPTRKISKIPFKVLDAPELQDDFYLNLVDW 195

Human   228 SSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAA 292
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 SSLNVLSVGLGTCVYLWSACTSQVTRLCDLSVEGDSVTSVGWSERGNLVAVGTHKGFVQIWDAAA 260

Human   293 GKKLSMLEGHTARVGALAWNAEQLSSGSRDRMILQRDIRTPPLQSERRLQGHRQEVCGLKWSTDH 357
            |||||:|||||||||||||||:|||||||||||||||||||.|||||||||||||||||||||||
  Rat   261 GKKLSVLEGHTARVGALAWNADQLSSGSRDRMILQRDIRTPALQSERRLQGHRQEVCGLKWSTDH 325

Human   358 QLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTG 422
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 QLLASGGNDNKLLVWNHSSLSPVQQYTEHLAAVKAIAWSPHQHGLLASGGGTADRCIRFWNTLTG 390

Human   423 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDG 487
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 QPLQCIDTGSQVCNLAWSKHANELVSTHGYSQNQILVWKYPSLTQVAKLTGHSYRVLYLAMSPDG 455

Human   488 EAIVTGAGDETLRFWNVFSKTRSTKVKWESVSVLNLFTRIR 528
            |||||||||||||||||||||||||   |||||||||||||
  Rat   456 EAIVTGAGDETLRFWNVFSKTRSTK---ESVSVLNLFTRIR 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FZR1	XP_016882352.1	WD40	<232..504	CDD:441893	268/271 (99%)
		WD40 repeat	264..301	CDD:293791	35/36 (97%)
		WD40 repeat	307..343	CDD:293791	33/35 (94%)
		WD40 repeat	348..384	CDD:293791	35/35 (100%)
		WD40 repeat	391..429	CDD:293791	37/37 (100%)
		WD40 repeat	434..472	CDD:293791	37/37 (100%)
		WD40 repeat	478..504	CDD:293791	25/25 (100%)
Fzr1	NP_001101544.2	WD40	<200..472	CDD:441893	268/271 (99%)
		WD40 repeat	232..269	CDD:293791	35/36 (97%)
		WD40 repeat	275..311	CDD:293791	33/35 (94%)
		WD40 repeat	316..352	CDD:293791	35/35 (100%)
		WD40 repeat	359..397	CDD:293791	37/37 (100%)
		WD40 repeat	402..440	CDD:293791	37/37 (100%)
		WD40 repeat	446..487	CDD:293791	40/43 (93%)